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Record W2150263331 · doi:10.15698/mic2015.07.215

Evolutionary rewiring of bacterial regulatory networks

2015· letter· en· W2150263331 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueMicrobial Cell · 2015
Typeletter
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicEvolution and Genetic Dynamics
Canadian institutionsUniversité de Moncton
FundersNational Institute of Food and AgricultureLeverhulme TrustBiotechnology and Biological Sciences Research CouncilDirectorate for Biological SciencesU.S. Department of Agriculture
KeywordsHorizontal gene transferGeneComputational biologyGene duplicationBiologyHomology (biology)Function (biology)GenomeGene regulatory networkSystems biologyGeneticsEvolutionary biologyGene expression

Abstract

fetched live from OpenAlex

Evolutionary rewiring of bacterial regulatory networks – – Mutational inactivation of two key genes in Pseudomonas fluorescens, a peptide synthase (viscB), which is involved in making a surfactant and enabling sliding motility, and the master regulator (fleQ) required for flagellum biosynthesis and swarming motility, produced a strain that was immotile on the surface of soft agar despite a perfectly functional flagellum regulon existing (...)

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.377
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0010.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.007
GPT teacher head0.197
Teacher spread0.190 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it