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Record W2151967875 · doi:10.1109/tuffc.2008.817

Microelastic imaging of bone

2008· review· en· W2151967875 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

fundA Canadian funder is recorded on the work.
no affNo Canadian affiliation: this work is invisible to an affiliation-only frame.
No Canadian affiliation. An affiliation-only frame, the usual design, would never have seen this work. It is one of the works that make the case for inverting the frame.

Bibliographic record

VenueIEEE Transactions on Ultrasonics Ferroelectrics and Frequency Control · 2008
Typereview
Languageen
FieldEngineering
TopicBone Tissue Engineering Materials
Canadian institutionsnot available
FundersUniversity of Windsor
KeywordsAmplitudeMaterials scienceReflection coefficientOpticsIsotropyTransverse planeAcousticsAcoustic microscopyCortical boneWavelengthReflection (computer programming)PhysicsMicroscopy

Abstract

fetched live from OpenAlex

Several high-frequency ultrasound techniques have been developed during the last decade with the intention of assessing elastic properties of bone at the tissue level. The basic measurement principles can be divided into: 1) measurement of the compressional wave velocity in thin tissue sections; 2) measurement of surface acoustic wave velocities in thick sections; and 3) derivation of the acoustic impedance from the confocal reflection amplitude in thick sections. In this paper, the 3 principles are described with example measurements given in the frequency range from 50 MHz to 1.2 GHz. The measurements were made with 2 microscopes operating in the pulse-echo mode, either with frequencies up to 200 MHz and time-resolved detection or between 100 MHz and 2 GHz and amplitude detection. The methods are compared and their application potentials and limitations are discussed with respect to the hierarchical structure of cortical bone. Mapping of the confocal reflection amplitude has superior capabilities for deriving quantitative elastic and structural parameters in the heterogeneous bone material. Even at low frequencies (50 MHz), the mineralized tissue matrix can be separated from the larger pores (Haversian canals), and the elastic coefficient in the probing direction can be measured in 2 dimensions. Depending on the type of sample surface preparation (flat or cylindrically shaped), local distribution of a single elastic coefficient or the average transverse isotropic stiffness tensor can be derived. With frequencies in the GHz range, the lamellar bone structure can be analyzed. However, at one GHz, the acoustic wavelength is still one order of magnitude larger than the individual mineralized collagen fibrils. Although the thickness of a lamellar unit can easily be assessed from the acoustic image, the derivation of the anisotropic elastic properties of the mineralized collagen fibrils as well as the detailed structure of a lamella can only be accomplished with further model assumptions.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Other design · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.973
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0020.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.012
GPT teacher head0.224
Teacher spread0.212 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it