MétaCan
Menu
Back to cohort
Record W2155177453 · doi:10.1255/ejms.433

Dissociation Reactions of Low-Energy Pentenyl Methyl Ether Radical Cations C <sub>5</sub> H <sub>9</sub> OCH <sub>3</sub> <sup>•+</sup>

2001· article· en· W2155177453 on OpenAlexaff
Richard D. Bowen, Moschoula A. Trikoupis, Johan K. Terlouw

Bibliographic record

VenueEuropean Journal of Mass Spectrometry · 2001
Typearticle
Languageen
FieldPhysics and Astronomy
TopicAdvanced Chemical Physics Studies
Canadian institutionsMcMaster University
FundersDivision of Materials Research
KeywordsChemistryOxonium ionDissociation (chemistry)IonBond-dissociation energyAllylic rearrangementEtherMedicinal chemistryStereochemistryOrganic chemistryCatalysis

Abstract

fetched live from OpenAlex

The dissociation chemistry of the low-energy C 5 H 9 OCH 3 •+ ions generated from the 13 isomeric pentenyl methyl ethers derived from stable alkenols has been studied. This was done by examining their metastable ion characteristics, in conjunction with 2 H and 13 C-labelling as well as collision-induced dissociation and neutralisation–reionisation experiments. The influence of the position and substitution pattern of the double bond on the chemistry of these C 6 H 12 O •+ species is considered. The closely similar reactions of C 2 H 5 CH=CHCH 2 OCH 3 •+ , 3 •+ , CH 2 =CH–CH(C 2 H 5 )OCH 3 •+ , 4 •+ , and CH 2 =C(C 2 H 5 )CH 2 OCH 3 •+ , 13 •+ , point to a common chemistry, which is rationalised in terms of facile 1,2-H and 1,2-C 2 H 5 shifts via distonic ions. Each of the other isomers displays a distinct, though often related, chemistry. The eight allylic ionised ethers easily lose CH 3 • to produce C 5 H 9 O + oxonium ions, whose structure was established by CID experiments; ions 3 •+ / 4 •+ / 13 •+ also readily expel C 2 H 5 • to give C 4 H 7 O + ions of structure CH 2 =CH–C + (H)OCH 3 . Elimination of CH 3 OH is also significant for 3 •+ / 4 •+ / 13 •+ and for (CH 3 ) 2 C=CHCH 2 OCH 3 •+ , 8 •+ , and CH 3 CH=C(CH 3 )CH 2 OCH 3 •+ , 11 •+ . Besides expelling CH 3 • and/or C 2 H 5 • and CH 3 OH, the three homoallylic isomers undergo dissociations which are (almost) absent for their allylic counterparts: thus, both CH 3 CH=CH(CH 2 ) 2 OCH 3 •+ , 2 •+ , and CH 2 =CH–CH(CH 3 )CH 2 OCH 3 •+ , 10 •+ , lose H • and H 2 O, whereas CH 2 =C(CH 3 )CH 2 CH 2 OCH 3 •+ , 7 •+ , is unique in predominantly losing CH 2 O. For the losses of CH 2 O and H 2 O mechanisms are proposed in which ion–neutral complexes of the type [C 5 H 10 •+ / CH 2 O] and [C 6 H 10 •+ / H 2 O] are key intermediates. The behaviour of the non-(homo)allylic isomer, CH 2 =CH(CH 2 ) 3 OCH 3 •+ , 1 •+ , is similar to that of 2 •+ but the reactions occur in different proportions. A mechanism for the facile loss of an alkyl radical from 1 + is proposed in which 1,4-H shifts and distonic ions as well as communication with ionised cyclopentyl methyl ether, 14 •+ , play an important role.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.004
Threshold uncertainty score0.014

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0040.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.009
GPT teacher head0.229
Teacher spread0.220 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations4
Published2001
Admission routes1
Has abstractyes

Explore more

Same venueEuropean Journal of Mass SpectrometrySame topicAdvanced Chemical Physics StudiesFrench-language works237,207