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Record W2156424776 · doi:10.1128/jcm.01145-07

Confirmatory Real-Time PCR Assay for Human Papillomavirus (HPV) Type 52 Infection in Anogenital Specimens Screened for HPV Infection with the Linear Array HPV Genotyping Test

2007· article· en· W2156424776 on OpenAlexafffund
François Coutlée, Danielle Rouleau, Georges Ghattas, Catherine Hankins, Sylvie Vézina, Pierre Côté, John Macleod, Alexandra de Pokomandy, Deborah Money, Sharon Walmsley, Hélène Voyer, Paul Brassard, Eduardo L. Franco

Bibliographic record

VenueJournal of Clinical Microbiology · 2007
Typearticle
Languageen
FieldMedicine
TopicCervical Cancer and HPV Research
Canadian institutionsToronto General HospitalUniversity of TorontoUniversity of British ColumbiaInstitut National de Santé Publique du QuébecMcGill UniversityCentre Hospitalier de l’Université de MontréalUniversité de MontréalHôpital Notre-Dame
FundersNational Cancer InstituteOntario HIV Treatment NetworkStyrelsen för Internationellt Utvecklingssamarbete
KeywordsGenotypingTypingHuman papillomavirusPapillomaviridaeVirologyHPV infectionPolymerase chain reactionBiologyReal-time polymerase chain reactionMolecular biologyGenotypeMedicineMicrobiologyGeneCervical cancerGeneticsInternal medicineCancer

Abstract

fetched live from OpenAlex

A novel real-time PCR assay for detection of human papillomavirus type 52 (HPV-52) DNA (RT-52) was evaluated on 265 anogenital samples. RT-52 had a sensitivity of 98.4% and a specificity of 100% compared to conventional HPV-52 typing assays, including hybridization of PGMY products with an HPV-52-specific probe and PCR sequencing of HPV-52 E6.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.006

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.002
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0010.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0020.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.078
GPT teacher head0.422
Teacher spread0.344 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations46
Published2007
Admission routes2
Has abstractyes

Explore more

Same venueJournal of Clinical MicrobiologySame topicCervical Cancer and HPV ResearchFrench-language works237,207