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Evaluation of Adverse Outcomes Requires the Correct Denominator

2006· letter· en· W2157749444 on OpenAlexaffabout
G. Allen Finley

Bibliographic record

VenueAnesthesia & Analgesia · 2006
Typeletter
Languageen
FieldHealth Professions
TopicPatient Safety and Medication Errors
Canadian institutionsIzaak Walton Killam Health CentreDalhousie University
Fundersnot available
KeywordsMedicineContext (archaeology)Adverse effectOpioidDosingDepression (economics)SAFERIntensive care medicineAnalgesicPatient satisfactionMEDLINEAnesthesiaInternal medicineSurgery

Abstract

fetched live from OpenAlex

To the Editor: Vila et al. (1) have appropriately questioned slavish adherence to treatment algorithms, even in the context of cancer pain management. They are also correct in suggesting that there are more factors to consider in analgesic dosing than a one-dimensional report of pain intensity and wisely advise that level of consciousness should be part of routine assessment. We would also support the use of pulse oximetry for patients receiving parenteral opioids, as is standard in many pediatric hospitals, especially during dose titration. However, I was disappointed in the absence of a key datum in their results: the number of patients, or patient days, on opioids. Although the total number of inpatient days has almost halved between the two time periods examined, I would not be surprised if opioid use had more than doubled. The fact that satisfaction scores increased suggests a dramatic change in care, as patients may be reluctant to report low satisfaction even with poor pain management (2). With no significant difference between adverse outcomes (and apparently decreased mortality), opioid use may actually be safer since the introduction of the “NPTA”. No one has ever suggested that opioids were risk-free, but pain also has adverse consequences, including, at least in theory, concerns that are specific to oncology (3,4). It may be appropriate to examine the risks and benefits of pain management in the context of all-cause morbidity and mortality, not merely the reported incidence of respiratory depression. G. Allen Finley, MD, FRCPC, FAAP Professor of Anesthesia and Psychology Senior Clinical Research Scholar Dalhousie University Medical Director Pediatric Pain Management IWK Health Centre Halifax, NS, Canada [email protected]

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.053
metaresearch head score (Gemma)0.346
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesnone
DomainCandidate signal: Methods · Consensus signal: none
Study designCandidate signal: Theoretical or conceptual · Consensus signal: none
GenreCandidate signal: Commentary · Consensus signal: Commentary
Teacher disagreement score0.947
Threshold uncertainty score0.278

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0530.346
Meta-epidemiology (narrow)0.0020.001
Meta-epidemiology (broad)0.0040.002
Bibliometrics0.0040.003
Science and technology studies0.0020.005
Scholarly communication0.0100.011
Open science0.0060.003
Research integrity0.0150.027
Insufficient payload (model declined to judge)0.0100.008

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.093
GPT teacher head0.402
Teacher spread0.309 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

Study designTheoretical or conceptual
DomainMethods
GenreCommentary

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2006
Admission routes2
Has abstractyes

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