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Record W2162247464 · doi:10.1093/ckj/sft052

Transient nephrogenic syndrome of inappropriate antidiuresis: Table 1.

2013· article· en· W2162247464 on OpenAlexaff
Ralph Kettritz, Daniel G. Bichet, Friedrich C. Luft

Bibliographic record

VenueClinical Kidney Journal · 2013
Typearticle
Languageen
FieldMedicine
TopicElectrolyte and hormonal disorders
Canadian institutionsHôpital du Sacré-Cœur de MontréalUniversité de Montréal
Fundersnot available
KeywordsMedicineIntensive care medicine

Abstract

fetched live from OpenAlex

The patient is a 56-year-old man who entered the hospital because of hyponatraemia. He observed problems with short-term memory, gait disturbances, and had fallen while going downstairs. He also claimed attention deficits and visual disturbances. He had been presented to his primary care physician who observed a low serum Na (102 mmol/L) and referred him for further diagnostic studies. The patient otherwise enjoyed stable health. He had undergone stent placement for coronary disease but had normal cardiac function. He ingested simvastatin and aspirin. Aside from some ibuprofen after a tooth extraction some weeks earlier, he had ingested no other tablets. He denied weight loss, any gastrointestinal symptoms and had not observed cough or shortness of breath. His blood pressure was 140/85 mmHg, heart rate 68/min. He was oriented in all spheres; his tandem walking and Romberg testing were slightly unstable, he had no oedema, and no other pertinent findings. The chest roentgenogram was normal. Computerized tomography suggested the presence of a gastric mass, which after an extensive workup, was resected. The lesion turned out to be a gastrointestinal stromal tumour (GIST). Laboratory findings are given in Table 1. We reasoned that this euvolemic patient had syndrome of inappropriate antidiuretic hormone (SIADH) related to the GIST. However, post-operatively the serum Na decreased to 117 mmol/L and the preoperative anti-diuretic hormone (ADH) measurement from admission was returned at 1.3 ng/L, a low value. The patient was discharged with tolvaptan 7.5 mg/day. We had occasion to test him briefly during tolvaptan treatment. With a serum Na of 142 mmol/L he ingested 1.5 L water over 20 min. His serum Na stayed stable at 140 mmol/L, while his urinary osmolarity fell to 101 mOsm/L with Na 14 and K 5 mmol/L.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.822
Threshold uncertainty score0.999

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.023
GPT teacher head0.308
Teacher spread0.285 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2013
Admission routes1
Has abstractyes

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