BioGRID: a general repository for interaction datasets
Why is this work in the frame?
A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.
Abstract
Access to unified datasets of protein and genetic interactions is critical for interrogation of gene/protein function and analysis of global network properties. BioGRID is a freely accessible database of physical and genetic interactions available at http://www.thebiogrid.org. BioGRID release version 2.0 includes >116 000 interactions from Saccharomyces cerevisiae, Caenorhabditis elegans, Drosophila melanogaster and Homo sapiens. Over 30 000 interactions have recently been added from 5778 sources through exhaustive curation of the Saccharomyces cerevisiae primary literature. An internally hyper-linked web interface allows for rapid search and retrieval of interaction data. Full or user-defined datasets are freely downloadable as tab-delimited text files and PSI-MI XML. Pre-computed graphical layouts of interactions are available in a variety of file formats. User-customized graphs with embedded protein, gene and interaction attributes can be constructed with a visualization system called Osprey that is dynamically linked to the BioGRID.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
The record
- Venue
- Nucleic Acids Research
- Topic
- Bioinformatics and Genomic Networks
- Field
- Biochemistry, Genetics and Molecular Biology
- Canadian institutions
- Ontario Institute for Cancer ResearchPrincess Margaret Cancer Centre
- Funders
- National Cancer InstituteCanadian Institutes of Health ResearchTerry Fox Foundation
- Keywords
- BiologyGraphical user interfaceVisualizationComputational biologyGene interactionDrosophila melanogasterSaccharomyces cerevisiaeUser interfaceComputer scienceGeneGeneticsData miningOperating system
- Has abstract in OpenAlex
- yes