Lipocalin-2: Response to a Progressive Treadmill Protocol in Obese and Normal-weight Men
Bibliographic record
Abstract
PURPOSE: Lipocalin-2 (Lcn2), a newer adipocyte-secreted acute phase protein, was recently reported to be correlated with potential effects on obesity and inflammation. The reaction of this protein to progressive exercise has not been evaluated yet. This study was designed to compare the serum Lcn2 and high-sensitivity C-reactive protein (hs-CRP) levels after participating in an acute bout of treadmill protocol in obese and normal-weight men. METHODS: NINE OBESE (AGED: 43.2±4.6 yrs and body mass index (BMI): 31.4±1.6 kg/m(2)) and 9 normal-weight (aged: 42.9±4.4 yrs and BMI: 23.03±1.7 kg/m(2); mean ± SD) sedentary men selected randomly from volunteers performed a single bout of exercise according to the treadmill Bruce protocol. RESULTS: Before the exercise, Lcn2 level was higher in obese than normal-weight individuals (P<0.05). A significant increase in Lcn2, hs-CRP, white blood cells (WBC) and insulin resistance index was observed after the exercise in both groups (P<0.05). The level of Lcn2, hs-CRP and WBC increase was more significant in obese individuals than normal-weight subjects after the exercise (P<0.05). CONCLUSIONS: It seems that the levels of Lcn2 and other inflammatory markers elevated in obese and normal-weight men after participating in an exhaustive progressive exercise. These changes in obese men were considerable.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".