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Record W2166411760 · doi:10.5539/ijb.v6n2p77

The Power-Law-Tail in the Distribution of the Nucleotides of Genomes Was Related to the Complexity of Organism: New Classification of Organisms

2014· article· en· W2166411760 on OpenAlexvenueno aff
Masaharu Takeda

Bibliographic record

VenueInternational Journal of Biology · 2014
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicFractal and DNA sequence analysis
Canadian institutionsnot available
Fundersnot available
KeywordsGenomeNucleotideBiologyOrganismBase pairBacterial genome sizeDNAGC-contentArchaeaPower lawGeneticsGeneMathematics

Abstract

fetched live from OpenAlex

We proposed a new index of the classification of organisms (cells) based on the appearance frequency of four nucleotides (bases) of various genomes. In double logarithmic plot of L (distance of a base to the next base, x-axis) vs F (frequencies of a base at L, y-axis), each value of four bases was expressed in y = ae-bx at L = 1 ~ 15, and y = Ux + W (power-law-tail) at L = more than 16 bases, respectively, in a single-strand of DNA. The a-, b- and U-values (slope) of four bases were resulted from the GC-content (%) and the size (nt) of the genome. Moreover, each value was identical as A to T, and as G to C, respectively, in one organism. The power-law-tail should be unique to the genomes of the same species, the eukaryotes, the prokaryotes. The eukaryotic genomes were essentially composed of great number of bases with plural long power-law-tail regions when compared with those of the prokaryotes. In the prokaryotes, the base-distribution was partitioned at L = 20, and the U-values (base-distribution in power-law-tail region) of the archaea were similar to the eukaryotes compared with those of the eubacteria. Thus, the power-law-tail of the genomic DNA should be come from the structural features of the cells, i.e., the size, the GC-content and other characteristics of the genomic DNA. These results indicated that the power-law-tail would be specific for the complexity of organisms in individual genome, and might be a new index for cells.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.005
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.005
Threshold uncertainty score0.010

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.005
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0050.003
Science and technology studies0.0010.002
Scholarly communication0.0020.004
Open science0.0010.001
Research integrity0.0010.002
Insufficient payload (model declined to judge)0.0010.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.016
GPT teacher head0.269
Teacher spread0.253 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2014
Admission routes1
Has abstractyes

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