The Effectiveness of Proctofoam-HC for Treatment of Hemorrhoids in Late Pregnancy
Bibliographic record
Abstract
Currently no topical anti-hemorrhoidal agents have been studied for effectiveness in pregnancy. This study evaluated the effectiveness of Proctofoam-HC used during the last trimester of pregnancy. In this prospective, open-label, observational study, pregnant women prescribed Proctofoam-HC were asked to complete two telephone interview questionnaires. A total of 88 women completed the study. All hemorrhoidal symptoms, including pain, pruritus, swelling, itching, decreased significantly (P < 0.001) and overall well-being improved. The improvement was clinically very significant after correction for potential placebo effect. Proctofoam-HC appears to provide effective treatment of hemorrhoids in late pregnancy. À l’heure actuelle, aucun agent anti-hémorroïdal topique n’a fait l’objet d’études quant à l’efficacité pendant la grossesse. Cette étude a évalué l’efficacité de Proctofoam-HC utilisé au cours du dernier trimestre de la grossesse. Dans le cadre de cette étude observationnelle, ouverte et prospective, on a demandé à des femmes enceintes auxquelles l’on avait prescrit du Proctofoam-HC de participer à deux entrevues téléphoniques. Au total, 88 femmes ont participé à l’étude. Tous les symptômes hémorroïdaux (y compris la douleur, le prurit, l’enflure et la démangeaison) ont connu une baisse significative (P < 0,001); de plus, le bien-être global a connu une amélioration. L’amélioration s’est avérée très significative sur le plan clinique à la suite de la neutralisation d’un possible effet placebo. Proctofoam-HC semble constituer un traitement efficace contre les hémorroïdes au cours des derniers stades de la grossesse.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".