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Escherichia coli K-12: a cooperatively developed annotation snapshot--2005

2006· article· en· 625 citations· W2167708455 on OpenAlex· 10.1093/nar/gkj405

Why is this work in the frame?

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

Canadian funderA Canadian agency funded it. The work may carry no Canadian affiliation at all.

No Canadian affiliation. An affiliation-only frame — the usual design — would never have seen this work. It is one of the works that make the case for inverting the frame.

Machine scores (provisional)

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Opus teacher head0.032
GPT teacher head0.312
Teacher spread
0.280 · how far apart the two teachers sit on this one work
Validation status
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Abstract

The goal of this group project has been to coordinate and bring up-to-date information on all genes of Escherichia coli K-12. Annotation of the genome of an organism entails identification of genes, the boundaries of genes in terms of precise start and end sites, and description of the gene products. Known and predicted functions were assigned to each gene product on the basis of experimental evidence or sequence analysis. Since both kinds of evidence are constantly expanding, no annotation is complete at any moment in time. This is a snapshot analysis based on the most recent genome sequences of two E.coli K-12 bacteria. An accurate and up-to-date description of E.coli K-12 genes is of particular importance to the scientific community because experimentally determined properties of its gene products provide fundamental information for annotation of innumerable genes of other organisms. Availability of the complete genome sequence of two K-12 strains allows comparison of their genotypes and mutant status of alleles.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

The record

Venue
Nucleic Acids Research
Topic
Bacterial Genetics and Biotechnology
Field
Biochemistry, Genetics and Molecular Biology
Canadian institutions
Funders
Core Research for Evolutional Science and TechnologyNational Institute of General Medical SciencesDirectorate for Biological SciencesMinistry of Education, Culture, Sports, Science and TechnologyUniversity of OxfordWellcome TrustGenome CanadaPurdue UniversityU.S. Department of EnergyNational Institutes of HealthNational Science Foundation
Keywords
BiologyGenomeGeneAnnotationGeneticsEscherichia coliSnapshot (computer storage)Genome projectComputational biologyWhole genome sequencingDatabase
Has abstract in OpenAlex
yes