Evidence of brain mitochondrial activities after oxygen inhalation by 31P magnetic resonance spectroscopy at 3T
Bibliographic record
Abstract
The purpose of this study was to explore mitochondrial activities after oxygen inhalation by 31P magnetic resonance spectroscopy. Six healthy volunteers were studied using a GE 3T scanner. A spin-echo MRS sequence was utilized with a GE service coil. TR was 2000 msec and TE 35 msec with 128 scan averages. Before 31P scan, a 1H MRS pre-scan was performed to obtain shimming values. Exact two 31P scans were performed before and after oxygen inhalation through nasal cannula at a flow rate of 10 L/min. Data were processed offline using the SAGE/IDL software. Peak integral values of inorganic phosphor, phosphocreatine, and ATPs were measured. Peak integral values of inorganic phosphor were decreased from 1.44% to 16.62% (mean+/-SD, 8.2+/-4.60). Peak integral values of phosphocreatine were increased from 1.06% to 8.64% (4.54+/-2.74). Peak integral values of gammaATP were increased from 0.75% to 15.97% (5.94+/-6.10); alphaATP from 1.21% to 16.05% (7.04+/-6.14); betaATP from 1.01% to 7.12% (3.08+/-2.30). Brain mitochondrial activities were increased and more ATPs were produced after oxygen inhalation in healthy volunteers.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.001 | 0.000 |
| Insufficient payload (model declined to judge) | 0.002 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".