Design of a fast-shaping amplifier for PET/CT APD detectors with depth-of-interaction
Bibliographic record
Abstract
An integrated 0.35-/spl mu/m CMOS fast-shaping amplifier has been designed for coincidence detection and zero-cross time pulse-shape discrimination (PSD) in positron emission tomography (PET) and for high-rate event counting in computerized tomography (CT) with avalanche photodiode (APD)-based detectors. Analytical simulations of CR-RC/sup n/ filters of various order and shaping time constant were carried out to optimize the timing performance, keeping in mind the stringent channel density requirements of the detector front-end electronics. The filter was implemented with the biquadratic bandpass architecture using a folded cascode transconductance amplifier. The electronic timing resolution of the coincidence circuit was 92 ps in the ideal case without an APD (C/sub in/ = 0 pF), and 243 ps with an APD (C/sub in/ = 30 pF). By comparison, the same system with the CMOS shaper replaced by an Ortec 579 Fast Filter Amplifier set to a shaping time of 10 ns yielded an electronic time resolution of 79 ps in the ideal case without capacitance and 236 ps with the APD. The 511-keV coincidence time resolution for a crystal scintillator-based lutetium oxyorthosilicate (LSO)-APD detector was measured to be 1.49 ns.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.001 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".