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Record W2181473625

Effects of MSG supplementation on free amino acids in plasma of growing-finishing Pigs

2012· preprint· en· W2181473625 on OpenAlexaff
Jun Zhang, Yulong Y. Yin, Q. He, Gang G. Chen, Tiejun T. Li, Xiaosong X. Wu, Martin M. Nyachoti, Francois F. Blachier, Yongfei Y. Wang, Qingqi Wen

Bibliographic record

VenueHAL (Le Centre pour la Communication Scientifique Directe) · 2012
Typepreprint
Languageen
FieldNursing
TopicBiochemical Analysis and Sensing Techniques
Canadian institutionsCanadian Society for Immunology
Fundersnot available
KeywordsStomachGlutamate receptorSmall intestineSplanchnicAmino acidMonosodium glutamateInternal medicineLumen (anatomy)GlutamineIntraperitoneal injectionAlanineStomach tubeEndocrinologyJejunumEnteral administrationChemistryBiologyBiochemistryParenteral nutritionMedicineAnatomyHemodynamics
DOInot available

Abstract

fetched live from OpenAlex

Glutamate is extensively metabolized in small intestine epithelial cells during its transcellular transfer from the lumen to bloodstream and after its uptake from the bloodstream. In order to study the effect of monosodium glutamate (MSG) supplementation given either by the parenteral route or by the enteral route on the circulating amino acid concentrations in growing-finishing pigs, animals received MSG at a dose equal to 0.25 g/kg body weight by intraperitoneal injection or by injection into the stomach. Up to 255 min, arterial and portal venous blood was collected and amino acid concentrations were measured. The results show that the glutamate concentrations in venous and arterial plasma increase rapidly after injection of MSG in stomach. However, glutamate concentration in both venous and arterial plasma was much higher after peritoneal than stomach injection. Aspartate and alanine concentrations in both venous and arterial plasma were higher after stomach than peritoneal injection. The results obtained are compatible with the view that i) a large part of glutamate in MSG is metabolized by the intestine in pigs; ii) at the dose used. MSG is, however, not entirely metabolized by the intestine and iii) glutamate metabolism in pig intestine leads to aspartate and alanine production.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.002
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.157
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0030.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.001
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.013
GPT teacher head0.245
Teacher spread0.232 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations7
Published2012
Admission routes1
Has abstractyes

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