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Record W2181579183 · doi:10.1109/biocas.2015.7348349

Inductively powered arbitrary-waveform adaptive-supply electro-optical neurostimulator

2015· article· en· W2181579183 on OpenAlexaff
Hossein Kassiri, Muhammad Tariqus Salam, Fu‐Der Chen, Behraz Vatankhahghadim, Nima Soltani, Michael Chang, Peter L. Carlen, Taufik A. Valiante, Roman Genov

Bibliographic record

Venuenot available
Typearticle
Languageen
FieldNeuroscience
TopicPhotoreceptor and optogenetics research
Canadian institutionsUniversity of Toronto
Fundersnot available
KeywordsWaveformVoltageElectromagnetic coilElectrical impedanceElectrical engineeringTransmitterOptogeneticsElectronic engineeringComputer scienceMaterials scienceEngineeringChannel (broadcasting)

Abstract

fetched live from OpenAlex

A hybrid current-mode and optogenetic miniature neurostimulating system is presented. The 16-channel electrical stimulator outputs arbitrary-waveform charge-balanced current-mode stimulation pulses with the amplitude ranging from 0.05mA to 10mA. To optimize power consumption, the supply voltage is automatically adjusted through an impedance monitoring feedback loop that gauges the minimum required headroom voltage. The 8-channel optogenetic stimulator reuses the arbitrary-waveform generation functions of the electrical stimulator. Each pulse-generator drives one LED with a maximum of 25mA. The LEDs are assembled within a custom-made 4×4 ECoG grid electrode array, which enables precise optical stimulation of neurons with a 300μm spatial resolution and simultaneous monitoring of the neural response by the ECoG electrode, at different distances of the stimulation site. The implantable system is a 3×2.5×1 cm3 stack of a receiver coil and two mini-boards. The power is received by a 32-layer flexible inductive coil and is regulated by the wireless communication board. The adaptive neurostimulator board boosts the regulated voltage up to the level set by the feedback loop with a maximum of 24V. The system also receives stimulation parameters wirelessly from the amplitude-shift-keyed power carrier. Both electrical and optogenetic stimulation results from chronic and acute in vivo rodent experiments are presented.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.131
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.135
GPT teacher head0.321
Teacher spread0.186 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations7
Published2015
Admission routes1
Has abstractyes

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