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Record W2194071725

Research Ethics and HIV/AIDS

2008· article· en· W2194071725 on OpenAlexaff
Bernard M. Dickens

Bibliographic record

VenueSSRN Electronic Journal · 2008
Typearticle
Languageen
FieldMedicine
TopicHepatitis B Virus Studies
Canadian institutionsUniversity of Toronto
Fundersnot available
KeywordsDeveloping countryHuman immunodeficiency virus (HIV)Medical researchPolitical scienceEconomic growthMedicineDevelopment economicsImmunologyEconomicsPathology
DOInot available

Abstract

fetched live from OpenAlex

The ethical implications of research into HIV infection and AIDS merit attention in their own right, but of related concern are the ethical implications of HlV infection and AIDS research that investigators in sponsoring international agencies and countries, principally in the developed world, plan and execute in host countries that are principally in the developing world. HlV/AIDS is now a universal phenomenon, but its burden, until recently most profoundly felt in countries of sub-Saharan Africa, especially East Africa, is spreading to countries of Asia that, like those of Africa, are ill-equipped to cope with its personal and economic effects. Within the general area of research with human subjects, concerns arise about how research on HlV infection and AIDS in particular, has affected popular understanding of the character of medical and wider health research. Trans-national research raises questions about the ethical sensitivities that have to be applied when investigators propose research studies on human subjects to be conducted in cultures with which they are unfamiliar, and when investigators from countries with relatively affluent economies intend to develop and implement. research among relatively resource-poor populations, in other countries. Countries with relative wealth often contain impoverished populations, among which HlV infection and AIDS may have an above-average incidence, but the focus of this paper will be on low-income populations in countries other than the investigators' own.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.186
metaresearch head score (Gemma)0.190
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesResearch integrity
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: none
Teacher disagreement score0.983
Threshold uncertainty score0.985

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.1860.190
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0020.001
Bibliometrics0.0020.003
Science and technology studies0.0100.084
Scholarly communication0.0160.009
Open science0.0020.008
Research integrity0.0170.018
Insufficient payload (model declined to judge)0.0060.002

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.088
GPT teacher head0.385
Teacher spread0.298 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2008
Admission routes1
Has abstractyes

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