Intense arousal of novel male mice in proximity to previously inseminated females: Inactivation of males via chlorpromazine does not diminish the capacity to disrupt pregnancy
Bibliographic record
Abstract
In the course of investigating early pregnancy disruptions by novel males, intense behavioral interactions and chemical emissions were observed among males housed in proximity to inseminated females. These interactions were evident despite wire-mesh separations between males and females. Experiments were designed to examine whether such arousal plays a role in pregnancy disruption. During the first 5 days of pregnancy, inseminated CF-1 strain female mice were either left undisturbed or exposed to novel outbred males. Physical separations between males did not diminish the frequency of pregnancy disruption. Subsequently, we investigated whether heavy sedation of novel males via chronic chlorpromazine administration would diminish the capacity to disrupt pregnancy. Pregnancy was disrupted to the same degree in females exposed to drug-treated males and those exposed to alert competing males given vehicle injections. These data show an unprecedented degree of arousal and pheromonal emission among competing males but suggest that these factors are not critical for the capacity to disrupt pregnancy.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.001 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".