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Evidence of a genetic link between endometriosis and ovarian cancer
Alice W. Lee, Claire Templeman, Douglas Stram, Jonathan Beesley, Jonathan P. Tyrer, Andrew Berchuck, Paul D.P. Pharoah, Georgia Chenevix‐Trench, Celeste Leigh Pearce, Roberta B. Ness, Agnieszka Dansonka‐Mieszkowska, Aleksandra Gentry‐Maharaj, Alexander Hein, Alice S. Whittemore, Allan Jensen, Andreas du Bois, Angela Brooks‐Wilson, Anja Rudolph, Anna Jakubowska, Anna H. Wu, Argyrios Ziogas, Arif B. Ekici, Arto Leminen, Barry P. Rosen, Beata Śpiewankiewicz, Beth Y. Karlan, Britton Trabert, Brooke L. Fridley, C. Blake Gilks, Camilla Krakstad, Catherine M. Phelan, Cezary Cybulski, Christine M. Walsh, Claus Høgdall, Daniel W. Cramer, David G. Huntsman, Diana Eccles, Diether Lambrechts, Dong Liang, Douglas A. Levine, Edwin S. Iversen, Elisa V. Bandera, Elizabeth M. Poole, Ellen L. Goode, Els Van Nieuwenhuysen, Estrid Høgdall, Fiona Bruinsma, Florian Heitz, Francesmary Modugno, Graham G. Giles, Harvey A. Risch, Helen Baker, Helga B. Salvesen, Heli Nevanlinna, Hoda Anton‐Culver, Honglin Song, Iain A. McNeish, Ian Campbell, Ignace Vergote, Ingo B. Runnebaum, Ingvild L. Tangen, Ira Schwaab, Jacek Gronwald, James Paul, Jan Lubiński, Jennifer A. Doherty, Jenny Chang‐Claude, Jenny Lester, Joellen M. Schildkraut, Jolanta Lissowska, Jolanta Kupryjańczyk, Joseph L. Kelley, Joseph H. Rothstein, Julie M. Cunningham, Karen Lu, Karen Carty, Kathryn L. Terry, Katja K.H. Aben, Kirsten B. Moysich, Kristine G. Wicklund, Kunle Odunsi, Lambertus A. Kiemeney, Lara Sucheston‐Campbell, Lene Lundvall, Leon F.A.G. Massuger, Liisa M. Pelttari, Linda E. Kelemen, Linda S. Cook, Line Bjørge, Lotte Nedergaard, Louise A. Brinton, Lynne R. Wilkens, Malcolm C. Pike, Marc T. Goodman, Maria Bisogna, Mary Anne Rossing, Matthias W. Beckmann, Matthias Dürst, Melissa C. Southey, Melissa Kellar, Michelle A.T. Hildebrandt, Nadeem Siddiqui, Natalia Antonenkova, Natalia Bogdanova, Nhu D. Le, Nicolas Wentzensen, Pamela J. Thompson, Patricia Harrington, Penelope M. Webb, Peter A. Fasching, Peter Hillemanns, Philipp Harter, Piotr Sobiczewski, Rachel Palmieri Weber, Ralf Bützow, Robert P. Edwards, Robert A. Vierkant, Rosalind Glasspool, Sandra Oršulić, Sandrina Lambrechts, Sara H. Olson, Shan Wang‐Gohrke, Shashi Lele, Shelley S. Tworoger, Simon A. Gayther, Stacey A. Missmer, Steven A. Narod, Susan J. Ramus, Susanne K. Kjær, Tanja Pejović, Thilo Dörk, Ursula Eilber, Usha Menon, Valerie McGuire, Weiva Sieh, Xifeng Wu, Yukie T. Bean, Yurii B. Shvetsov
Bibliographic record
VenueFertility and Sterility · 2015
Typearticle
Languageen
FieldMedicine
TopicEndometriosis Research and Treatment
Canadian institutionsnot available
FundersNational Institute of Environmental Health SciencesNational Cancer InstituteCancer Council TasmaniaCancer Council QueenslandCancer Council NSWCancer Council VictoriaNational Health and Medical Research CouncilNational Center for Advancing Translational SciencesMedical Research CouncilCanadian Institutes of Health ResearchUniversität UlmHelse VestOvarian Cancer Research FundCancer AustraliaEuropean CommissionLon V. Smith FoundationU.S. Public Health ServiceRutgers Cancer Institute of New JerseyWorkSafeBCBundesministerium für Bildung und ForschungNational Institute for Health and Care ResearchHelsingin ja Uudenmaan SairaanhoitopiiriFred C. and Katherine B. Andersen FoundationMayo Foundation for Medical Education and ResearchFrancis Crick InstituteNational Institutes of HealthNorges ForskningsrådCancer Research UKMinnesota Ovarian Cancer AllianceNational Center for Research ResourcesRoswell Park Cancer InstituteCancer Council South AustraliaDeutsches Krebsforschungszentrum
KeywordsOvarian cancerEndometriosisOncologySerous fluidMedicineSerous carcinomaCancerInternal medicine
Abstract
No abstract in any covered source. Its absence is recorded, not treated as a negative.
No abstract. This is not a gap in this database; OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.
How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.005
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.213
Threshold uncertainty score0.607
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.005 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
Opus teacher head0.159
GPT teacher head0.378
Teacher spread0.220 · how far apart the two teachers sit on this one work
Validation status
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".
Quick stats
Citations55
Published2015
Admission routes1
Has abstractno