Line tension of multicomponent bilayer membranes
Why this work is in the frame
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Bibliographic record
Abstract
The line tension or edge energy of bilayer membranes self-assembled from binary amphiphilic molecules is studied using self-consistent-field theory (SCFT). Specifically, solutions of the SCFT equations corresponding to an infinite membrane with a circular pore, or an open membrane, are obtained for a coarse-grained model in which the amphiphilic species and hydrophilic solvents are represented by ABandED diblock copolymers and C homopolymers, respectively. The edge energy of the membrane is extracted from the free energy of the open membranes. Results for membranes composed of mixtures of symmetric and cone- or inverse cone-shaped amphiphilic molecules with neutral and/or repulsive interactions are obtained and analyzed. It is observed that an increase in the concentration of the cone-shaped species leads to a decrease of the line tension. In contrast, adding inverse cone-shaped copolymers results in an increase of the line tension. Furthermore, the density profile of the copolymers reveals that the line tension is regulated by the distribution of the amphiphiles at the bilayer edge.
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Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it