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Record W2265529440

Hemodialysis of the Future: Prolonged and/or Frequent Dialysis

2002· article· en· W2265529440 on OpenAlexaboutno aff
Sung-Feng Wen

Bibliographic record

VenueActa Nephrologica · 2002
Typearticle
Languageen
FieldMedicine
TopicDialysis and Renal Disease Management
Canadian institutionsnot available
Fundersnot available
KeywordsHemodialysisMedicineDialysisModalitiesIntensive care medicineHyperphosphatemiaQuality of life (healthcare)SurgeryInternal medicineKidney disease
DOInot available

Abstract

fetched live from OpenAlex

Despite recent advances in hemodialysis (HD) technology. The overall outcome of patients on conventional HD remains miserably unsatisfactory with a 5-year patient survival rate of 30% in the United States. In search of better HD modalities, a number of investigators in Europe and North America have reported greatly improved outcome with prolonged and/or frequent RD. These include 8h, 3-times-weekly HD from Tassin, France, every-other-day or 4-times-weekly HD from Lecce, Italy, Short daily HD (SDHD) from Perugia, Italy, and nocturnal HD (NHD) from Toronto, Canada, with increasing number of other SDHD and NHD programs reported in recent years. The prolonged and/or frequent HD allows better clearance of solutes, smooth ultrafiltration with good control of hypertension, avoidance of solute rebound and disequilibrium symptoms, liberalization of diet with improved nutrition, and better neuro-cognitive function. In addition, NHD is associated with correction of hyperphosphatemia without the use of phosphate binders, improved removal of middle molecules such as β2 microglobulin, and effective control of sleep apnea. Above all, in all of these HD modalities, patient survival is remarkably improved with reduction in hospitalization, and the better quality of life leads to good rehabilitation. Although these reports are based on anecdotal experiences, many with selected groups of patients, the impressive improvement in patient outcome makes it worthwhile to further pursue large scale controlled studies for confirmation as well as for the future guide to improve HD modalities.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.480
Threshold uncertainty score0.999

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.019
GPT teacher head0.229
Teacher spread0.210 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designNot applicable
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2002
Admission routes1
Has abstractyes

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