The relationship between blood pressure and arterial characteristics in clinically normotensive children
Bibliographic record
Abstract
Atherosclerosis is the major cause of cardiovascular disease. In adults, elevated blood pressure (BP) is recognized as a major risk factor for atherosclerotic progression. In children the relationship between elevated BP and atherosclerosis progression is less understood. The objective of this study was to examine differences in central arterial distensibility (DIST) and intima‐media thickness (IMT) as well as systemic pulse transit time (PTT) in normal blood pressure (NBP) and elevated blood pressure (EBP) children. The sample consisted of 104 children (21 EBP, 83 NBP) aged 11–14 years. Blood pressure was clinically normal (on two separate occasions); however, the EBP had a significantly elevated BP in comparison to their NBP counterparts. We assessed PTT, IMT, and DIST using applanation tonometry, ultrasonography of the common carotid artery, electrocardiography, and toe pulse oximetry. No significant differences were found between NBP and EBP for IMT (0.42(0.06) vs. 0.43(0.05) mm, respectively) or DIST (65.3(27.6) kPa −1 x10 −3 vs. 62.7(21.2) kPa −1 x10 −3 , respectively). PTT was significantly elevated in the EBP group (341(23) ms) vs. the NBP (321(25) ms) group. Children 11–14 years of age with elevated BP do not show central arterial changes yet systemic vascular tone appears to be elevated. Heart and Stroke Foundation of Canada
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.003 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.001 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.001 | 0.001 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".