MétaCan
Menu
← Back to cohort
Record W2274636564 · doi:10.7287/peerj.preprints.556v1

Systematic review of the statistical scope used in studies based on skeletal muscle autophagy and exercise

2014· preprint· en· W2274636564 on OpenAlexaff
Diane Brownlee

Bibliographic record

Venuenot available
Typepreprint
Languageen
FieldMedicine
TopicAutophagy in Disease and Therapy
Canadian institutionsYork University
Fundersnot available
KeywordsScope (computer science)Skeletal muscleAutophagyCredibilityStatistical analysisStatistical hypothesis testingBioinformaticsMedicinePhysiologyComputer scienceBiologyStatisticsInternal medicineMathematicsBiochemistry

Abstract

fetched live from OpenAlex

Skeletal muscle reaction to exercise is an essential are of research due to its ongoing prevalence in disease research and general health. It is well documented that under exercise conditions, biogenesis and autophagy increase. One main component of this pathway are lysosomes, the essential cellular clearance machine. Statistical analyses used to analyze these data have been sustained over the years. The objective of this systematic review is to compare and contrast the different methods used for analyzing data in molecular exercise physiology. Upon investigating the research papers the majority of the papers used either a t-test or an ANOVA as their primary statistical analyses, used 41% and 64% of the time, respectively. All other statistical tests were used a maximum of 9% of the time. Another trend that was evident was the increased utilization of post hoc tests in the more recent papers compared to earlier papers. This could provide interesting evidence into the credibility of the results reported and provide more insight into the research in molecular exercise physiology.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.094
metaresearch head score (Gemma)0.411
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesnone
DomainCandidate signal: Methods · Consensus signal: none
Study designCandidate signal: Systematic review · Consensus signal: Systematic review
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.906
Threshold uncertainty score0.497

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0940.411
Meta-epidemiology (narrow)0.0030.002
Meta-epidemiology (broad)0.0150.022
Bibliometrics0.0300.032
Science and technology studies0.0010.003
Scholarly communication0.0060.004
Open science0.0030.004
Research integrity0.0020.002
Insufficient payload (model declined to judge)0.0070.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.024
GPT teacher head0.334
Teacher spread0.311 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

Study designSystematic review
DomainMethods
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2014
Admission routes1
Has abstractyes

Explore more

Same topicAutophagy in Disease and Therapy→French-language works237,207→