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Metabolic syndrome in healthy, multiethnic adolescents in Toronto: the use of fasting blood glucose as a simple indicator

2010· article· en· W2289723150 on OpenAlexaffabout
Vladimir Vuksan, Alexander L. Rogovik, Valentina Peeva, Uljana Beljan‐Zdravkovic, Mark Stavro, Alexandra L. Jenkins, André H. Dias, Sudi Devanesen, Christopher Fairgrieve, Amir Hanna

Bibliographic record

VenueThe FASEB Journal · 2010
Typearticle
Languageen
FieldMedicine
TopicDiabetes, Cardiovascular Risks, and Lipoproteins
Canadian institutionsUniversity of TorontoSt. Michael's Hospital
Fundersnot available
KeywordsMedicineWaistMetabolic syndromeBlood pressurePost-hoc analysisInternal medicineStepwise regressionAnalysis of covarianceCircumferenceLinear regressionObesityStatisticsMathematics

Abstract

fetched live from OpenAlex

Objectives To assess the presence of metabolic syndrome (MetS) features in healthy, normal‐weight, multiethnic adolescents and to determine whether fasting blood glucose (FBG) may be a simple indicator of its presence. Methods A cross‐sectional study using a convenience sample of secondary school students. GLM ANCOVA adjusted for multiple pairwise comparisons by the post hoc Tukey‐Kramer test was used to assess differences among the tertiles of FBG. Results A total of 182 adolescents from 62 Greater Toronto Area (GTA) secondary schools were recruited (44% Caucasian, 34% South Asian, and 22% Chinese), with mean(SD age 17.4±0.9 years, BMI 22.1±3.4 kg/m2, and FBG 4.92±0.4 mmol/L. Analysis with GLM ANCOVA across the tertiles of FBG (3.83–4.78 mmol/L, 4.79–5.08 mmol/L, and 5.09–6.45 mmol/L) showed significant linear increases of BMI (p<0.005), waist circumference (p<0.001), systolic blood pressure (p<0.001), and diastolic blood pressure (p<0.05) with increasing FBG. Stepwise multiple regression analysis indicated systolic blood pressure and waist circumference as independent predictors of the increased FBG level. Conclusions MetS markers are present in a sample of healthy multiethnic adolescents in GTA. FBG could be used as a simple indicator of MetS to allow for early detection of MetS presence and introduction of preventive lifestyle measures.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.670
Threshold uncertainty score0.000

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0010.000
Scholarly communication0.0010.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.024
GPT teacher head0.282
Teacher spread0.258 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2010
Admission routes2
Has abstractyes

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