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Record W2289877044 · doi:10.14288/1.0098175

Avian brainstem and descending spinal projections associated with locomotion

2010· article· en· W2289877044 on OpenAlexaboutno aff
Deirdre M. S. Webster

Bibliographic record

VenuecIRcle (University of British Columbia) · 2010
Typearticle
Languageen
FieldNeuroscience
TopicHemispheric Asymmetry in Neuroscience
Canadian institutionsnot available
Fundersnot available
KeywordsBrainstemPhysical medicine and rehabilitationNeuroscienceMedicineBiology

Abstract

fetched live from OpenAlex

Electrical microstimulation studies in the decerebrate bird have previously identified brainstem regions that play a role in the initiation of locomotion. This thesis was designed to identify the neuroanatomical connections of these physiologically defined locomotor regions. The experiments were conducted on the Pekin duck, Anas platyrhynchos; Canada goose, Branta canadensis; Sulphur-crested cockatoo, Cacatua galerita; and Eastern rosella, Platycercus eximius. A variety of retrograde tracer chemicals (e.g. wheat germ agglutinin-horseradish peroxidase and fluorescent tracer True Blue) were injected into either the cervical or lumbar spinal cord alone or in conjunction with a more rostral subtotal lesion of the spinal cord to determine (1) the origins of spinal projections to the spinal cord, and (2) the funicular organization of these pathways at the lumbar level. The distribution of retrogradely labelled neurones was similar in all avian species examined. There were no direct telencephalic projections to the spinal cord. Descending brainstem-spinal spinal pathways from previously identified "locomotor sites" in the ventromedial medulla (nucleus reticularis medullaris centralis and nucleus reticularis, gigantocellularis) projected to the lumbar level via the ventrolateral funiculus, whereas dorsolateral "locomotor sites" (nucleus reticularis parvocellularis, nucleus and descending tract of the trigeminal nerve) only projected as far as the cervical spinal cord. The afferent projections to these identified brainstem locomotor regions were determined by discrete injections of retrograde fluorescent tracers into the ventromedial or dorsolateral pontomedullary locomotor sites. Afferent input originated principally from the pontomedullary reticular formation and the mesencephalon. The similarity of avian spinal and brainstem connections to those previously described for mammals indicates considerable conservation of the origins and organization of descending locomotor pathways between mammalian and non-mammalian species.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.896
Threshold uncertainty score0.949

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0010.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.014
GPT teacher head0.196
Teacher spread0.182 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2010
Admission routes1
Has abstractyes

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