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Record W2290183784 · doi:10.1093/ofid/ofu052.1133

1587Prescription erectile dysfunction medication, sexual risk behaviors, and sexually transmitted infections among HIV positive men

2014· article· en· W2290183784 on OpenAlexaff
Jose Pablo Heudebert, C. Maya Tong, Ashutosh Tamhane, Edward W. Hook, Nicholas Van Wagoner, Jodie Dionne‐Odom, James L. Raper, Greer Burkholder

Bibliographic record

VenueOpen Forum Infectious Diseases · 2014
Typearticle
Languageen
FieldMedicine
TopicSexual function and dysfunction studies
Canadian institutionsUniversity of British Columbia
Fundersnot available
KeywordsMedicineErectile dysfunctionHuman immunodeficiency virus (HIV)Men who have sex with menSexually activeSexual dysfunctionSexual behaviorClinical psychologyPsychiatryFamily medicineSyphilis

Abstract

fetched live from OpenAlex

Background. Use of erectile dysfunction (ED) medication, particularly recreational use, has been associated with sexual risk behaviors and sexually transmitted infections (STIs). Data on prescription ED medication use, sexual risk behaviors and STI screening among HIV+ men are lacking. Methods. A cross-sectional study at a university-based HIV clinic evaluated prevalence and correlates of ED medication prescription among established male HIV+ patients in 2011-12. Patients were included if ≥19 years old, in care for >1 year, with at least 2 visits ≥90 days apart within the last year. Multivariable (MV) log-binomial regression models were used to evaluate associations (prevalence ratio, PR with 95% confidence interval, CI) of patient characteristics with ED medication prescription. Results. Of 1,170 HIV+ men, 269 (23%) were prescribed ED medication (mean age 50, 27% heterosexual and 73% MSM, 41% African American). Similar prevalence of ED medication prescription was observed for MSM (22%) and heterosexual men (26%). Among men on ED medications who took a survey regarding current sexual risk behavior, 181/234 (77%) reported multiple partners, 57/144 (40%) sex without condom use and 73/230 (32%) sex after alcohol/drug use. In MV analysis, age ≥ 50 years (PR = 1.5; 95% Cl 1.2-1.8), multiple sexual partners (1.9; 1.4-2.5), sex after alcohol/drugs (1.3; 1.0-1.7), and prior history of STI (1.4; 1.1-1.7) were significantly associated with ED medication prescription, while sexual orientation, race, insurance, substance use, and viral load were not. Annual protocol-driven syphilis testing was done in 253/269 (94%) of men on ED medication, with 9 (4%) positive for new infection. In contrast providers performed less annual testing for Neisseria gonorrhoeae (GC) and Chlamydia trachomatis (CT): 83/269 (31%), of whom 3 were GC positive and 1 CT positive. Among MSM on ED medication (n = 196), GC/CT testing was done in 55 (28%), of whom 54 received urogenital testing and 14 rectal testing. Conclusion. In this cross-sectional study, ED medication prescription was significantly associated with sexual risk behavior in HIV+ men. Incidence of syphilis among men on ED medications was high. Screening for GC and CT needs to be increased, particularly rectal screening among MSM. Disclosures. All authors: No reported disclosures.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.069
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0010.000
Scholarly communication0.0000.001
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.009
GPT teacher head0.262
Teacher spread0.254 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2014
Admission routes1
Has abstractyes

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