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Effect of prior heavy exercise on O2 uptake kinetics in the upper regions of the moderate‐intensity domain

2008· article· en· W2294050351 on OpenAlexaffabout
John M. Kowalchuk, Harry B. Rossiter, Lisa M. K. Chin, Donald H. Paterson, Brian J. Whipp

Bibliographic record

VenueThe FASEB Journal · 2008
Typearticle
Languageen
FieldMedicine
TopicCardiovascular and exercise physiology
Canadian institutionsWestern University
Fundersnot available
KeywordsKineticsIntensity (physics)Cycle ergometerChemistryAnimal scienceInternal medicineCardiologyMedicineHeart ratePhysicsBiologyBlood pressure

Abstract

fetched live from OpenAlex

That pulmonary O 2 uptake (VO 2 ) kinetics in the upper region of the moderate‐intensity exercise domain are slow relative to the lower region is thought to reflect an intrinsic characteristic of the recruited muscles (Brittain et al., EJAP 86:125, 2001). Because prior heavy exercise speeds moderate‐intensity VO 2 kinetics when they are slow, we wished to determine whether prior heavy exercise would similarly speed VO 2 kinetics in the upper moderate‐intensity domain. Ten males performed 4–6 repeats of two double‐step (S) cycle ergometer protocols: 1) S1‐S2: 20 W to 80% of the estimated lactate threshold made in two equal increments, and 2) HS1‐HS2: as protocol 1, but with S2 preceded by heavy exercise (Δ50%); each step lasted 6 min. VO 2 was measured breath‐by‐breath using a turbine and mass spectrometer. The fundamental VO 2 time constant (τ) was greater (p<0.05) in S2 (41 ± 15 s) than S1 (21 ± 4 s). After heavy exercise, τVO 2 was lower (p<0.05) in HS2 (31 ± 10 s) than S2, but remained greater (p<0.05) than HS1 (22 ± 5 s). Thus VO 2 kinetics in the upper moderate‐intensity domain are not immutable, becoming faster after heavy exercise. However, this effect (presumably due to activation of intramuscular enzymes, improved oxidative substrate provision and/or improved O 2 transport kinetics) did not entirely overcome the intrinsically‐slow kinetics in this region. Supported by NSERC, Canada; Wellcome Trust, UK

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.003
Threshold uncertainty score0.010

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.001
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0030.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.016
GPT teacher head0.250
Teacher spread0.234 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2008
Admission routes2
Has abstractyes

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