A Study on Clinical Effect of Combined Pulsed Dye Laser And Intralesional Triamcinolone Acetonide in the Treatment of Keloid
Bibliographic record
Abstract
Keloids are common and cause functional and psychological morbidity. A wide variety of treatments, all in current usage, indicate that no treatment has been shown to be markedly superior to the others. This study was done using pulsed dye laser followed by more traditional intralesional steroid injection in the treatment of keloid. The aim of this study was to determine the effectiveness of the PDL in combination with intralesional triamcinolone acetonide (TCA) in the treatment of keloid and to elucidate possible side effects and complications. A prospective clinical trial was done in the Department of Dermatology & Venereology, Combined Military Hospital, Dhaka Cantonment, Dhaka, from December 2013 to February 2014. Adult patients of both sexes (Fitzpatric skin type IV & V) aged between 15 and 50 years with varying degree of keloids were randomly selected for the study. In this single-blinded clinical trial, 50 patients were randomly assigned and was irradiated by 595-nm flashlamp-pumped pulsed-dye laser (PDL, 5-7.5 J/cm2) at the 1st,4th, and 8th weeks and Intralesional steroid was given following PDL. Lesions were assessed for vascularity, pliability, pigmentation and height. The study showed an excellent improvement in nearly all measures, Good to excellent improvements (>76% improvement) were reported by 93% patient. Vancouver scar scale (0-14) decreased from 12.17 to a post treatment value of 3.41which is an excellent achievement. Results were reported by the blinded observer as follows: in vascularity (from 2.7 to 0.61), in pliability (from 3.9 to 1.1), in hyperpigmentation (from 2.4 to 0.92), in height (from 2.87 to 0.78).J Dhaka Medical College, Vol. 23, No.2, October, 2014, Page 234-238
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.001 |
| Meta-epidemiology (narrow) | 0.001 | 0.000 |
| Meta-epidemiology (broad) | 0.002 | 0.001 |
| Bibliometrics | 0.001 | 0.000 |
| Science and technology studies | 0.000 | 0.001 |
| Scholarly communication | 0.000 | 0.001 |
| Open science | 0.001 | 0.000 |
| Research integrity | 0.001 | 0.001 |
| Insufficient payload (model declined to judge) | 0.003 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".