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Record W2300515179 · doi:10.1016/j.kint.2016.01.014

Advanced chronic kidney disease populations have elevated trimethylamine N-oxide levels associated with increased cardiovascular events

2016· article· en· W2300515179 on OpenAlexafffund
Richard B. Kim, Bridget L. Morse, Ognjenka Djurdjev, Mila Tang, Norman Muirhead, Brendan J. Barrett, Daniel T. Holmes, François Madore, Catherine M. Clase, Claudio Rigatto, Adeera Levin, Mohsen Agharazii, Joanne Blouin, France Samson, Ayub Akbarii, Judy O. Cheesman, Jennilea Courtney, Sabrina Hamer, Edita Delic, Valerie Cronin, Paul E. Barré, Jeffrey A. Golden, Elizabeth Langille, Sylvia Adams, Janet Morgan, Cathy Moreau, Susan M. Cooper, Brian Forzley, Susan Caron, Shauna Granger, Susan Valley, Helen Sather, Serge Cournoyer, Lorraine Ménard, Michèle Roy, Hélène Skidmore, Dolores Beaudry, Janis M. Dionne, Josephine Chow, Valla Sahraei, Sandra Donnelly, Niki Dacouris, Rosa M. Marticorena, Brenda R. Hemmelgarn, Sharon Gulewich, Troy Hamilton, Paul Keown, Nadia Zalunardo, Daniel A. Rogers, Reena Tut, M. Paquette, Rossitta Yung, Nancy Ferguson, Helen Chiu, Kathleen Carlson, Lina Sioson, Taylor Perry, Zainab Sheriff, Naama Rozen, Charmaine E. Lok, Michelle Cross, Cathy Forrester, Alexandra Cotoi, Manon Maltais, Louise Moist, Kerri Gallo, Sarah Langford, Leah Slamen, Danielle Cram, Mary Jeanne Edgar, Cameron Edgar, Karen E. GROENEWEG, Eileen M. McKinnon, Erin McRae, Kyla Blackie, Bharat Nathoo, Kimmy Lau, Malvinder S. Parmar, Sylvie Gélinas, Martine Leblanc, Lucie Lépine, Dolores Friesen, Steven D. Soroka, Susan Fleet, Jeanette Squires, Siva Thanamayooran, Michael Binder, Christine Hines, Brenda McNeil, Patrice McDougall, Howard Joy, Deborah Gillis, Kathleen Hines, Sheldon W. Tobe, Mary Chessman, Nancy Perkins, Martha Agelopoulos, Stacey Knox, Tiffany Richards, Marcello Tonelli, Susan K. Szigety, Dawn Opgenorth, Karen Yeates, Karen Mahoney

Bibliographic record

VenueKidney International · 2016
Typearticle
Languageen
FieldMedicine
TopicDialysis and Renal Disease Management
Canadian institutionsProvidence Health CareUniversity of ManitobaUniversité de MontréalMemorial University of NewfoundlandUniversity of British ColumbiaMcMaster UniversityLondon Health Sciences CentreWestern University
FundersCanadian Institutes of Health Research
KeywordsTrimethylamine N-oxideHazard ratioInterquartile rangeKidney diseaseMedicineInternal medicineConfidence intervalRenal functionProspective cohort studyQuartileRisk factorGastroenterologyEndocrinologyTrimethylamineBiologyBiochemistry

Abstract

fetched live from OpenAlex
No abstract in any covered source. Its absence is recorded, not treated as a negative.

No abstract. This is not a gap in this database; OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.003
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.244
Threshold uncertainty score0.999

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.003
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.021
GPT teacher head0.274
Teacher spread0.253 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations175
Published2016
Admission routes2
Has abstractno

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