Gestational weight gain, prepregnancy body mass index and offspring attention‐deficit hyperactivity disorder symptoms and behaviour at age 10
Bibliographic record
Abstract
Objective To assess offspring attention‐deficit hyperactivity disorder ( ADHD ) symptoms and emotional/behavioural impairments at age 10 years in relation to maternal gestational weight gain ( GWG ) and prepregnancy body mass index ( BMI ). Design and setting Longitudinal birth cohort from Magee‐Womens Hospital, Pittsburgh, Pennsylvania (enrolled 1983–86). Population Mother–infant dyads ( n = 511) were followed through pregnancy to 10 years. Methods Self‐reported total GWG was converted to gestational‐age‐standardised z ‐scores. Multivariable linear and negative binomial regressions were used to estimate effects of GWG and BMI on outcomes. Main outcome measures Child ADHD symptoms were assessed with the Conners’ Continuous Performance Test. Child behaviour was assessed by parent and teacher ratings on the Child Behaviour Checklist ( CBCL ) and Teacher Report Form, respectively. Results The mean ( SD ) total GWG (kg) was 14.5 (5.9), and 10% of women had a pregravid BMI ≥30 kg/m 2 . Prepregnancy obesity ( BMI of 30 kg/m 2 ) was associated with increased offspring problem behaviours including internalising behaviours (adjusted β 3.3 points, 95% CI 1.7–4.9), externalising behaviours (adjusted β 2.9 points, 95% CI 1.4–4.6), and attention problems (adjusted β 2.3 points, 95% CI 1.1–3.4) on the CBCL , compared with normal weight mothers ( BMI of 22 kg/m 2 ). There were nonsignificant trends towards increased offspring impulsivity with low GWG among lean mothers (adjusted incidence rate ratio 1.2, 95% CI 0.9–1.5) and high GWG among overweight mothers (adjusted incidence rate ratio 1.7, 95% CI 0.9–2.8), but additional outcomes did not differ by GWG z ‐score. Results were not meaningfully different after excluding high‐substance users. Conclusions In a low‐income and high‐risk sample, we observed a small increase in child behaviour problems among children of obese mothers, which could have an impact on child behaviour in the population. Tweetable abstract Maternal obesity is associated with a small increase in child behaviour problems.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.002 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.001 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.001 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.002 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".