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Record W2305876893 · doi:10.1093/annonc/mdw062

Long-course oxaliplatin-based preoperative chemoradiation versus 5 × 5 Gy and consolidation chemotherapy for cT4 or fixed cT3 rectal cancer: results of a randomized phase III study

2016· article· en· W2305876893 on OpenAlexaff
Krzysztof Bujko, Lucjan Wyrwicz, Andrzej Rutkowski, Małgorzata Malinowska, Lucyna Pietrzak, J Kryński, Wojciech Michalski, Janusz Olędzki, Jerzy Kuśnierz, Leszek Zając, M. Bednarczyk, Marek Szczepkowski, Wiesław Tarnowski, Ewa Kosakowska, Jakub Zwoliński, Mariola Winiarek, Katarzyna Wiśniowska, M. Partycki, K. Bęczkowska, Wojciech Polkowski, Roman Styliński, Ryszard Wierzbicki, Paweł Bury, M. Jankiewicz, Krzysztof Paprota, M. Lewicka, Bogumiła Ciseł, Magdalena Skórzewska, Jerzy Mielko, Marek Bębenek, Adam Maciejczyk, Bartosz Kapturkiewicz, A. Dybko, Łukasz Hajac, Andrzej Wojnar, Tadeusz Lesniak, J. Zygulska, D. Jantner, Ewa Chudyba, W. Zegarski, Manuela Las‐Jankowska, Michał Jankowski, L Kołodziejski, A. Radkowski, U. Żelazowska-Omiotek, B. Czeremszyńska, Lucyna Kępka, Jarosław Kołb-Sielecki, Z. Toczko, Zbys Fedorowicz, Adam Dziki, Adrian Danek, G Nawrocki, Rafał Sopyło, W. Markiewicz, Piotr Kędzierawski, Jerzy Wydmański, J. Albiński, Renata Banaś, E. Chmielowska, Wiesław Bal, J. Baszczyk-Mnich, Marcin Białas, T. Borowiec, Anna Cencelewicz, Konstanty Chomik, Maciej Chwaliński, I. Ciepela, Dorota Dupla, Artur Florek, A. Górnicki, Krzysztof Jeziorski, Wojciech Jóźwicki, Jarek Kobiela, Masahiko Koda, P Kołodziej, Piotr Kruszewski, Mariusz Kryj, G. Kuciel-Lisiecka, Robert Kwiatkowski, Angela Lachowski, Piotr Liszka-Dalecki, Adam Majewski, Wojciech Majewski, T Majsak, Doualla-Bell Kotto Maka, Marcin Malka, Adam Mazurkiewicz, Jan Morawiec, E. Nogal, M. Olejniczak, D. Olkowski, Krystyna Ostrowska-Cichocka, Mariusz Pietruszka, G. Piotrkowski, M Plewicka, Dorota Porzuczek-Zuziak, Joanna Reszke, Anna Rychter, J. Sadowski, Andrzej Sałata, Krystyna Serkies, Ewa Śrutek, Bartosz Szostak, T. Tuziak, Dariusz Tyralik, Jacek Skoczylas, E. Wachua, Piotr Wandzel, B. Winkler-Spytkowska, Piotr Wojtasik, Konrad Wroński, M. Zemal, Ireneusz Zygulski

Bibliographic record

VenueAnnals of Oncology · 2016
Typearticle
Languageen
FieldMedicine
TopicColorectal Cancer Surgical Treatments
Canadian institutionsJuravinski Hospital
Fundersnot available
KeywordsMedicineOxaliplatinColorectal cancerBolus (digestion)Randomized controlled trialUrologyToxicityChemotherapyClinical endpointRadiation therapySurgeryCumulative incidenceNuclear medicineGastroenterologyInternal medicineCancerCohort

Abstract

fetched live from OpenAlex
No abstract in any covered source. Its absence is recorded, not treated as a negative.

No abstract. This is not a gap in this database; OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Randomized trial · Consensus signal: Randomized trial
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.004
Threshold uncertainty score0.013

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0020.002
Meta-epidemiology (narrow)0.0020.001
Meta-epidemiology (broad)0.0030.002
Bibliometrics0.0000.001
Science and technology studies0.0010.002
Scholarly communication0.0010.002
Open science0.0020.001
Research integrity0.0020.004
Insufficient payload (model declined to judge)0.0040.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.100
GPT teacher head0.452
Teacher spread0.352 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designRandomized trial
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations444
Published2016
Admission routes1
Has abstractno

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