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Record W2306650334 · doi:10.1093/biosci/biv190

The Hitchhiker's Guide to Quant Biology

2016· article· en· W2306650334 on OpenAlexaff
Arun S. Moorthy

Bibliographic record

VenueBioScience · 2016
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicGenetics, Bioinformatics, and Biomedical Research
Canadian institutionsUniversity of Guelph
Fundersnot available
KeywordsBiologyZoology

Abstract

fetched live from OpenAlex

The inclusion of quantitative methods to supplement, enhance, and even guide experimental inquiry has become imperative in biological research. With advances in techniques and technology, biological studies produce large amounts of unique data that can be understood only through the collaborative efforts of skilled data scientists and biologists themselves. As with any collaboration, the success rate of the collaborating groups is contingent on the ability of all parties to effectively communicate ideas and results. Using R at the Bench: ­Step-by-Step Data Analytics for Biologists, by Martina Bremer and Rebecca W. Doerge, is a resource that helps facilitate that communication process. It is not only a guidebook for biologists looking to strengthen their data-analytics understanding but also a broad reference to biology-specific scenarios that can benefit statisticians and data scientists alike. Bremer and Doerge convey an important message within their short—but necessary—second chapter describing the common pitfalls with statistical analysis in biology. The placement of this message near the front of their text was essential and reminded me why a comprehensive guidebook such as theirs has value to our quantitative biology community. Many of the ideas, such as the list of common mistakes or sources of variation, will come off as obvious to an experienced quantitative biologist or statistician. I find, however, that these apparently obvious ideas are often the most difficult to articulate, so having them listed in a concise manner with well-placed examples will provide me an excellent resource to tap into prior to conversations with collaborators.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.010
metaresearch head score (Gemma)0.025
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Commentary · Consensus signal: none
Teacher disagreement score0.058
Threshold uncertainty score0.195

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0100.025
Meta-epidemiology (narrow)0.0050.006
Meta-epidemiology (broad)0.0060.004
Bibliometrics0.0060.007
Science and technology studies0.0030.005
Scholarly communication0.0080.008
Open science0.0090.005
Research integrity0.0070.025
Insufficient payload (model declined to judge)0.0580.078

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.021
GPT teacher head0.330
Teacher spread0.309 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreCommentary

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2016
Admission routes1
Has abstractno

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