Effects of Long-term Oral Administration of Fluoride on the Physico-chemical Properties of Porcine Bone Mineral: Comparison between Cortical and Trabecular Bones.
Bibliographic record
Abstract
本研究では, 生後8カ月から14カ月の期間にNaF含有飲料水 (2mgF/kg体重/day) を与えたブタ (および, 同期間にわたり脱イオン水を摂飲した対照群動物) を対象として, フッ素の長期経口投与による骨の化学組成, 結晶性, 骨結晶の熱力学的な溶解度への影響を検討した. 観察試料として, 大腿骨骨幹部皮質骨と腰椎海綿骨の粉末試料を作成した. 骨試料の分析には, 顕微X線法と形態計測, X線回折法, FTIR, EPMA, 固相試料と溶液試料の化学分析を併用し, 骨結晶の溶解度測定は25℃, 1.8%CO-54分圧下で行った. 今回の実験結果から, 実験群動物の皮質骨でのF含有量は対照群に比べて一桁高く, 皮質骨と海綿骨とを比べると, 対照群・実験群ともに海綿骨で約2倍程度にまで濃縮されていたが, 組織学的には有意の差は検出されなかった. X線回折線の半値幅の測定から, 両群試料の間でc軸方向の結晶性には有意な差はなかったが, 実験群皮質骨試料ではa, b軸方向での結晶性の向上が認められた. 骨結晶の溶解度に関して, ハイドロキシアパタイトの化学組成式に従った平衡時の溶液相でのイオン活量積として表すと, 対照群試料では皮質骨と海綿骨を問わず10-53から5×10-53, 実験群試料では一桁下がった10-54から5×10-54の範囲の値が得られた.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.001 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".