A Summary of the 2006 American Society for Colposcopy and Cervical Pathology Consensus Guidelines for the Management of Women With Abnormal Cervical Histologic Findings
Bibliographic record
Abstract
The American Society for Colposcopy and Cervical Pathology guidelines for the management of biopsy-proven cervical intraepithelial neoplasia (CIN) and adenocarcinoma in situ were recently updated and include significant modifications. Management recommendations are not based purely on the histologic diagnosis. Instead, management is determined using information from a number of sources including previous Papanicolaou test history, clinical setting, colposcopic findings, biopsy result, and any human papillomavirus testing. Nevertheless, biopsy interpretation remains a key determinant of management. Women with CIN 1 who have low-grade referral cytology (atypical squamous cells of undetermined significance, atypical squamous cells cannot exclude high-grade squamous intraepithelial lesion [SIL], or low-grade SIL) should be followed up only with cytology or human papillomavirus testing regardless of whether the colposcopic examination is satisfactory. Treatment is no longer acceptable (in contrast to the 2001 guidelines), unless the preceding cytology is high grade (high-grade SIL or atypical glandular cells not otherwise specified). Minor modifications, including an option of immediate loop electrosurgical excision, were made for the management of women with cervical intraepithelial neoplasia grades 2 and 3 (CIN 2, 3). Management recommendations for adolescents with any histologic diagnosis of CIN are conservative. During pregnancy, follow-up without treatment is recommended for CIN 1, 2, and 3 unless invasion is identified. The 2006 guidelines also include management recommendations for biopsy-confirmed adenocarcinoma in situ.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.002 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.001 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".