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Record W2323424559 · doi:10.1021/om000231e

Ruthenium Dihydride RuH<sub>2</sub>(PPh<sub>3</sub>)<sub>2</sub>((<i>R</i>,<i>R</i>)-cyclohexyldiamine) and Ruthenium Monohydride RuHCl(PPh<sub>3</sub>)<sub>2</sub>((<i>R</i>,<i>R</i>)-cyclohexyldiamine):  Active Catalyst and Catalyst Precursor for the Hydrogenation of Ketones and Imines

2000· article· en· W2323424559 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueOrganometallics · 2000
Typearticle
Languageen
FieldChemistry
TopicAsymmetric Hydrogenation and Catalysis
Canadian institutionsUniversity of Toronto
Fundersnot available
KeywordsRutheniumHeterolysisChemistryHydrideMedicinal chemistryDihydrogen complexStereochemistryBase (topology)HydrogenCatalysisOrganic chemistry

Abstract

fetched live from OpenAlex

The new monohydride RuHCl(PPh 3 ) 2 ( R, R -cydn), with base added, and dihydride RuH 2 (PPh 3 ) 2 ( R, R -cydn), in the absence of base, catalyze the hydrogenation of a wide variety of ketones and some imines at 3 atm of H 2 and 20 °C with high turnover numbers. The mechanism is thought to involve the concerted dihydrogen transfer from cis hydride and N−H groups to the substrate followed by heterolytic dihydrogen splitting.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.002
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Science and technology studies, Scholarly communication, Research integrity
Consensus categoriesMeta-epidemiology (narrow)
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.076
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0020.002
Meta-epidemiology (narrow)0.0040.004
Meta-epidemiology (broad)0.0040.002
Bibliometrics0.0020.006
Science and technology studies0.0020.003
Scholarly communication0.0010.003
Open science0.0020.001
Research integrity0.0020.002
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.008
GPT teacher head0.205
Teacher spread0.198 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it