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Record W2323973286 · doi:10.1136/sti.2010.046771

Reaching for the STARHS

2010· letter· en· W2323973286 on OpenAlexaboutno aff
Robert S. Remis

Bibliographic record

VenueSexually Transmitted Infections · 2010
Typeletter
Languageen
FieldMedicine
TopicHIV/AIDS Research and Interventions
Canadian institutionsnot available
Fundersnot available
KeywordsMedicineIncidence (geometry)SeroconversionCohortHuman immunodeficiency virus (HIV)AttritionFamily medicineDemographyPathology

Abstract

fetched live from OpenAlex

Measuring HIV incidence is critical to monitoring and, in the long run, controlling HIV infection in populations at risk worldwide. The serologic testing algorithm for recent HIV seroconversion (STARHS) assay allows one, under the right conditions, to determine HIV incidence from a single specimen. This approach is both elegant and exciting, since it can yield estimates of incidence in many situations where cohort studies are not feasible. Longitudinal cohort studies follow initially uninfected persons over time but are expensive, time-consuming and subject to biases related to selective recruitment and attrition as well as intervention effect which make their interpretation problematic. White and colleagues have recently published two reports in Sexually Transmitted Infections which examine an important issue in the application of STARHS.1 2 To help realise the enormous potential of such an approach, the WHO formed an international working group following a special session of the International AIDS Conference in Toronto in 2006. This WHO Working Group on HIV Incidence Assays recently published a comprehensive review of the progress made in the last 10 years and the substantial challenges remaining.3 In addition, UNAIDS recently launched the High Commission on HIV Prevention to reinvigorate HIV prevention worldwide; the Commission has already expressed a strong interest in promoting and exploiting improvements in …

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesResearch integrity, Insufficient payload (model declined to judge)
Consensus categoriesResearch integrity
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Commentary · Consensus signal: Commentary
Teacher disagreement score0.325
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0000.000
Science and technology studies0.0010.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0010.009
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.029
GPT teacher head0.328
Teacher spread0.299 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; both teacher heads agree on what is shown here.

Study designNot applicable
Domainnot available
GenreCommentary

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2010
Admission routes1
Has abstractyes

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