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Record W2325591260 · doi:10.1097/wnp.0b013e3182570f58

Prognosis of EEG Findings in Infancy

2012· article· en· W2325591260 on OpenAlexaff
Salah Almubarak, Peter K. H. Wong

Bibliographic record

VenueJournal of Clinical Neurophysiology · 2012
Typearticle
Languageen
FieldMedicine
TopicEpilepsy research and treatment
Canadian institutionsBC Children's HospitalUniversity of British Columbia
Fundersnot available
KeywordsElectroencephalographyEpilepsyIctalMedicinePediatricsAudiologyAnesthesiaPsychologyPsychiatry

Abstract

fetched live from OpenAlex

OBJECTIVE: To determine how specific early EEG abnormalities correlate with clinical outcome on long-term follow-up for neurological and epilepsy outcomes. Our aim was to revisit how early EEG abnormalities should be weighed for prognosis. METHODS: This is a retrospective study of 358 infants who had EEGs taken between 3 and 12 months of age and subsequent clinical assessment between 4 to 18 years of age. RESULT: Of the 358 infants, 215 had unfavorable neurological outcome (UNO), and 234 had epilepsy on follow-up. Breakdown: 117 had major abnormal EEG background of which 86% had UNO and 75% had epilepsy. One hundred had abnormal sleep potentials of which 89% had UNO and 80% had epilepsy. One hundred seventy-five had interictal epileptiform activity of which 80% had UNO and epilepsy. Sixty had ictal epileptiform activity of which 90% had UNO and 86% had epilepsy. One hundred ninety-two had markedly abnormal overall EEG impression of which 80% had UNO and 79% had epilepsy. CONCLUSIONS: Occurrence of significant EEG abnormalities in the first year was clearly associated with UNO and epilepsy. Current views that certain EEG abnormalities (e.g., interictal spike) may have little prognostic significance would need to be revisited.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.002
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.011
Threshold uncertainty score0.268

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.088
GPT teacher head0.444
Teacher spread0.355 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2012
Admission routes1
Has abstractyes

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