Autonomic mediation of the interdependence between variability signals of heart rate and blood pressure in the lizard <i>Gallotia galloti</i>
Bibliographic record
Abstract
Autonomic nervous system (ANS) involvement in the mediation of the synchronization between beat-to-beat RR interval variability (RRIV) and systolic blood pressure variability (SBPV) signals of the lizard Gallotia galloti (Oudart, 1839) was investigated through linear and nonlinear time series analysis methods in a pharmacological blockade context. The ANS blockers used were atropine, prazosin, and propranolol. The interdependence between the signals was quantified by means of the magnitude-squared coherence (MSC), which measures amplitude and phase linear synchronization; the phase lag index (PLI), which evaluates the phase synchronization; and the index L, which quantifies the generalized linear and nonlinear synchronization. Atropine decreased the PLI in the low-frequency (LF: 0.01–0.05 Hz) range; prazosin decreased the MSC in the medium-frequency (MF: 0.06–0.15 Hz) range; and propranolol did not alter any of the interdependence measures. It is suggested that (i) the cholinoceptor activity mediates the phase cardiovascular synchronization in the LF range; (ii) the α1-adrenoceptor activity mediates the amplitude and phase linear cardiovascular synchronization in the MF range; and (iii) the β-adrenoceptor activity plays no role in mediating any dynamics of cardiovascular synchronization in the studied frequency range. When comparing these results with those in mammals, a lesser overall autonomic involvement in the mediation of the studied cardiovascular interdependences is seen in reptiles.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".