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Record W2327499990 · doi:10.1016/j.gheart.2014.03.1913

PT133 Ischaemic times and adverse outcomes in STEMI stratified by glomerular filtration rate

2014· article· en· W2327499990 on OpenAlexaff
Jaya Chandrasekhar, Michel Lemay

Bibliographic record

VenueGlobal Heart · 2014
Typearticle
Languageen
FieldMedicine
TopicGlaucoma and retinal disorders
Canadian institutionsUniversity of Ottawa
Fundersnot available
KeywordsMedicineGynecology

Abstract

fetched live from OpenAlex

Il était de comparer les résultats pressionnels à un an postopératoire avec le MicroShunt® d'InnFocus avec ou sans chirurgie de la cataracte associée, selon différents emplacements et concentrations de la MMC.Il s'agit d'une étude rétrospective sur deux centres avec deux chirurgiens (France et République dominicaine).Les adultes devant bénéficier d'une chirurgie filtrante pour glaucome chronique à angle ouvert ont bénéficié d'un MicroShunt® sur un œil. L'effet de la concentration et du lieu d'application de la MMC a été étudié sur la PIO et sur la diminution du nombre de collyres anti-glaucomateux à un an.Quatre-vingt-sept yeux ont été étudiés avec un suivi d'un an. Vingt-trois yeux traités avec de la MMC à une concentration de 0,4 mg/mL près du limbe ont eu une baisse de PIO de 55 %, passant de 23,8 ± 5,3 mmHg en préopératoire à 10,7 ± 2,8 mmHg à un an. Le nombre de molécules hypotonisantes par patient a été diminué de 85 %, passant de 2,4 ± 0,9 à 0,3 ± 0,8. Trente et un yeux traités avec de la MMC à une concentration de 0,2 mg/mL près du limbe ont eu une baisse de PIO de 52 %, passant de 27,9 ± 6,7 mmHg en préopératoire à 13,3 ± 3,3 mmHg à un an. Le nombre de molécules hypotonisantes par patient a été diminué de 88 %, passant de 2,5 ± 1,4 à 0,5 ± 1,0. Trente-trois yeux traités avec de la MMC à une concentration de 0,4 mg/mL loin du limbe ont eu une baisse de PIO de 38 %, passant de 25,4 ± 7,9 mmHg en préopératoire à 15,7 ± 4,6 mmHg à un an. Le nombre de molécules hypotonisantes par patient a été diminué de 72 %, passant de 2,9 ± 1,0 à 0,8 ± 1,3. Il n'y a pas eu de complications menaçant la fonction visuelle.Le MicroShunt® d'InnFocus est une chirurgie filtrante dont l'efficacité dépend de la localisation et de la concentration de la MMC utilisée.To compare intraocular pressure (IOP) at one year with the InnFocus MicroShunt® with or without cataract surgery with according to placement and concentration of mitomycin C (MMC)A retrospective two-center, two-surgeon study (France and Dominican Republic).Adults with POAG requiring filtering surgery. One MicroShunt® was placed in one eye of each patient. The effect of concentration and site of application of MMC was assessed by IOP and medication reduction at one year.Eighty-seven eyes were studied with one-year follow-up. Twenty-three eyes treated with 0.4 mg/mL MMC close to the limbus demonstrated a 55% reduction in IOP from 23.8 ± 5.3 at baseline to 10.7 ± 2.8 mmHg at one year. Topical glaucoma medication/patient was reduced 85% from 2.4 ± 0.9 to 0.3 ± 0.8. Thirty-one eyes treated with 0.2 mg/mL MMC close to the limbus demonstrated a 52% reduction in IOP from 27.9 ± 6.7 at baseline to 13.3 ± 3.3 mmHg at one year. Topical glaucoma medication/patient was reduced 88% from 2.5 ± 1.4 to 0.5 ± 1.0. Thirty-three eyes treated with 0.4 mg/mL MMC deep in the pocket demonstrated a 38% reduction in IOP from 25.4 ± 7.9 at baseline to 15.7 ± 4.6 mmHg at one year. Topical glaucoma medication/patient was reduced 72% from 2.9 ± 1.0 to 0.8 ± 1.3. There were no sight-threatening long-term adverse events.The InnFocus MicroShunt® is a filtering surgery whose efficacy is related to the location of application and concentration of MMC used.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.008
Threshold uncertainty score0.409

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.006
GPT teacher head0.255
Teacher spread0.249 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations0
Published2014
Admission routes1
Has abstractyes

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