Ca2+‐related proteins associated with intracellular stores in rat lymphatics
Bibliographic record
Abstract
Calcium plays essential roles in the contraction of striated and smooth muscle types. Changes in cytoplasmic concentration of Ca 2+ depend in general on the calcium channels and pumps at the cytoplasmic and endoplasmic/sarcoplasmic reticulum membrane. As we have shown previously, lymphatic muscle has a unique combination of the striated and smooth muscle contractile and regulatory proteins (Muthuchamy et al., 2003). However, very little is known about the composition of the Ca 2+ ‐channels and pumping structures in the intracellular stores of lymphatic muscle. Our immunohistochemistry data with confocal microcopy from whole isolated vessels preparation, frozen sections and lymphatic muscle cell culture demonstrates the presence of inositol 1,4,5‐triphosphate receptor type 3 (IP3R3) channels, Ca 2+ transporting ATPase type 2a1 (SERCA2a1) and Ca 2+ transporting ATPase type 2a2 (SERCA2a2) at intracellular stores of rat mesenteric lymphatic vessels, cervical lymphatics and thoracic duct. Supported by NIH HL096552
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.001 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.001 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.002 | 0.001 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".