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Record W2328565322 · doi:10.1093/shm/hks126

Joe Sornberger, Dreams and Due Diligence: Till and McCulloch's Stem Cell Discovery and Legacy

2012· article· en· W2328565322 on OpenAlexaboutno aff
Jane Maienschein

Bibliographic record

VenueSocial History of Medicine · 2012
Typearticle
Languageen
FieldArts and Humanities
TopicHistory of Science and Medicine
Canadian institutionsnot available
Fundersnot available
KeywordsDiligenceStem cellSociologyLawMedia studiesClassicsHistoryEnvironmental ethicsPolitical sciencePsychologyPhilosophyBiologySocial psychology

Abstract

fetched live from OpenAlex

Joe Sornberger wants people to know about the important contribution by Canadians Jim Till and ‘Bun’ McCulloch to stem cell science and medicine. He asserts that they deserve far more credit than they have received, and draws on interviews with a number of their students and colleagues to make that point. The book is a mix of introduction to the work and polemical advocacy for its importance, and much less a scholarly social history. The emphasis on asserting Canadian leadership in stem cell science does not mean that the book does not have merit. It is often worth looking at less familiar historical episodes and reflecting on their impacts. Sornberger gives us a short book that might better have been a tightly organised essay. The structure leads to considerable redundancy, so that we read the same thing over and over. The strongest sections look at the way James Edgar Till and Ernest Armstrong McCullough came together to study stem cells in mice. We read (repeatedly) that the two were very different, though each embraced mathematical and physical approaches to medical questions. Together, they carried out experiments with radiation of mouse bone marrow cells and gradually came to see the implications of the work.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesScience and technology studies
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.746
Threshold uncertainty score0.998

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.005
Scholarly communication0.0000.001
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.036
GPT teacher head0.234
Teacher spread0.198 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designNot applicable
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2012
Admission routes1
Has abstractyes

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