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Record W2331062764 · doi:10.1177/1947603513479606

Current Trends in Cartilage Science

2013· article· en· W2331062764 on OpenAlexaboutno aff
Jos Malda, C. Wayne McIlwraith

Bibliographic record

VenueCartilage · 2013
Typearticle
Languageen
FieldMedicine
TopicOsteoarthritis Treatment and Mechanisms
Canadian institutionsnot available
FundersDutch Arthritis Association
KeywordsCartilageBasic researchRegeneration (biology)MedicineClinical scienceEngineering ethicsPolitical scienceMedical educationAlternative medicineLibrary sciencePathologyComputer scienceEngineeringAnatomyBiology

Abstract

fetched live from OpenAlex

From May 12 to 15, 2012, the 10th world congress of the International Cartilage Repair Society (ICRS) was held in Montreal, Canada.This year, there were 850 participants with backgrounds in both basic scientific as well as clinical research directed at cartilage repair and regeneration.It encompassed more than 135 oral and 270 poster contributions; 7 plenary sessions and 20 special sessions were organized (three in parallel), each of which included two to three invited lectures by international leaders in the field, covering recent developments and opinions both in clinical as well as more basic scientific research on cartilage repair.This year's program also included two honorary lectures.Prof.Joseph Buckwalter, who was also awarded the Genzyme lifetime achievement award, gave the first lecture elucidating underlying causes of posttraumatic osteoarthritis (OA) including measurement of articular surface impact energy (which correlates to the occurrence of posttraumatic OA), incongruity of the joint, 1 and instability of the joint.Research includes restoring congruity using computed tomography scans and developing a model to see how pieces fit together and evaluation of how reactive oxygen species (ROS), produced by the mitochondria and expressed after impaction, cause damage in the first 48 hours (and matrix components over a longer period of time) and could be addressed with a number of promising therapies (biologicals, distraction, etc.).Prof. Daniel Grande gave the second honorary lecture, in honor of his seminal work in the field of cartilage repair.He spoke about the history and genealogy of the autologous chondrocyte implantation technology, as well as the evolution of histology grading scales and cartilage imaging.He concluded that the field is going toward in situ tissue engineering, and he acknowledged the impact of the ICRS on improved standardized protocols for research and clinical application.Both Prof.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.194
Threshold uncertainty score0.948

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.019
GPT teacher head0.287
Teacher spread0.268 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2013
Admission routes1
Has abstractyes

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