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Record W2331666744 · doi:10.1542/pir.33-11-e72

Visual Diagnosis: Abnormal Nails in an Infant

2012· article· en· W2331666744 on OpenAlexaffabout
Natalie Cunningham, Peter J. Green

Bibliographic record

VenuePediatrics in Review · 2012
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicSkin and Cellular Biology Research
Canadian institutionsDalhousie University
Fundersnot available
KeywordsMedicinePediatrics

Abstract

fetched live from OpenAlex

1. Natalie P. Cunningham* 2. Peter J. Green, FRCP† 1. *Dalhousie University, Halifax, NS, Canada. 2. †Department of Medicine (Dermatology), Capital District Health Authority and Dalhousie University, Halifax, NS, Canada. * Abbreviations: ACE: : angiotensin-converting enzyme NPS: : nail patella syndrome A dermatologist has been following a 3-year-old girl for unusually shaped fingernails noted at birth. Her history is as follows. At age 6 months, the patient’s primary care physician referred her to the dermatology service after the child’s adoptive mother expressed concern about her daughter’s small, misshapen fingernails. The infant was born after a pregnancy complicated by maternal smoking. She was induced at term due to failure to progress and eventually required vacuum extraction, weighing 2.405 kg at birth with Apgar scores of 9 and 9 at 1 and 5 minutes, respectively. There had been no concerns with her growth or development, and she was an active and happy child. She took no medications and had no known allergies. Her family history included a biological mother with attention-deficit/hyperactivity disorder and substance abuse and a healthy maternal half-brother. Little was known about the biological father, but the biological mother indicated that the father had abnormal nails. Physical examination at 6 months revealed an alert, well-appearing infant in no acute distress. Vital signs were within normal limits for her age, and she was growing between the 50th and 75th percentiles for height, weight, and head circumference. She was normal in appearance. There were no dysmorphic features on her head, face, or torso. Her fingers were slightly tapered with normal creases. The nails of her fingers on both hands were small and unusually shaped with longitudinal grooving, most pronounced on her thumbnails and less so on the nails of the fifth digits. Her toenails were unaffected. Given the nonspecific nail features, the dermatologist recommended seeing the infant 1 year later. At age …

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.422
Threshold uncertainty score0.492

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.026
GPT teacher head0.360
Teacher spread0.334 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2012
Admission routes2
Has abstractyes

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