Late-onset Deep Infectious Keratitis After Descemet Stripping Endothelial Keratoplasty With Vent Incisions
Why this work is in the frame
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Bibliographic record
Abstract
PURPOSE: To report the clinical and histopathological findings of 3 cases of late-onset deep infectious keratitis after Descemet stripping endothelial keratoplasty (DSEK) with vent incisions. METHODS: From a retrospective review of 150 consecutive patients who underwent uncomplicated DSEK with vent incisions, 3 patients developed late-onset deep infectious keratitis. RESULTS: In case 1, the patient suffered a Pseudomonas corneal ulcer at the nasal vent incision after a dacryocystorhinostomy with stent, 16 months after DSEK. In case 2, a Streptococcus pneumoniae infection developed at the inferior vent incision from a spastic entropion 3 months after surgery. In case 3, an Enterococcus faecalis corneal ulcer presented as a deep stromal abscess in the nasal vent incision 7 weeks after DSEK. All cases required full-thickness penetrating keratoplasties. Visual acuities at the last follow-up were counting fingers (case 1), 20/80 (case 2), and 20/400 (case 3). CONCLUSIONS: Vent incisions in DSEK may allow bacterial keratitis to penetrate deeply leading to aggressive keratolysis. One must be cautious in using vent incisions in patients with increased bacterial flora and patients with poor ocular surface healing from systemic, local, or mechanical conditions. If vent incisions are performed, a midperipheral oblique incision, parallel to the limbus, with meticulous detail to wound construction is recommended.
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Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.002 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it