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Record W2334006210 · doi:10.5649/jjphcs.35.722

Survey on Usage of Dye Pharmaceutical Preparations in Sentinel Lymph Node Biopsy

2009· article· en· W2334006210 on OpenAlex
Kyohei Watanabe, Kayo Nomura, Fumiko Otsu, Nobuyuki Goto, Noriyuki Suda, Katsuhiko Matsuura, Yasunori Miyazaki, Masayuki Yamakawa, M. Yamaguchi, Kazuhiro Watanabe, Toshiaki Nakamura, Mikio Masada

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueIryo Yakugaku (Japanese Journal of Pharmaceutical Health Care and Sciences) · 2009
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicBreast Cancer Treatment Studies
Canadian institutionsHealth Care Foundation
Fundersnot available
KeywordsSentinel lymph nodeMedicineBiopsyLymphGeneral surgeryInternal medicinePathologyCancer

Abstract

fetched live from OpenAlex

Sentinel lymph node biopsy (SLNB) has recently been accepted as a standard diagnostic procedure in the treatment of early breast cancer.However, since there are no dyes for this diagnostic technique on the market in Japan, we conducted a survey of the situation of dye use and preparations for SLNB in regional cancer treatment centers.We sent a questionnaire to 286 institutions for which the response rate was 75.2%.The results showed that 80.9% of the institutions had already introduced SLNB and the dye-guided method was used by more than 90% of them.The most common indication for SLNB was breast cancer.Patent blue prepared by hospitals and indigo carmine and indocyanine green (both off-label use) were commonly used dye preparations for SLNB.Although patent blue is the most satisfactory dye and has the highest identification rate, problems were reported with hospital preparations.There were also differences between institutions regarding storage conditions, validity dates, preparation standards and annual use of this dye.The survey also revealed that 74.4% of institutions wanted dyes for SLNB to be marketed and there were numerous opinions on which types of patent blue preparation should be available.In conclusion, the present study indicated that there was a need for SNLB dye preparations in clinical practice and that it would be beneficial to make such preparations available on the market.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.062
Threshold uncertainty score0.548

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.057
GPT teacher head0.420
Teacher spread0.363 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it