Age-Specific Lipid and Lipoprotein Thresholds for Adolescents
Bibliographic record
Abstract
Plasma lipid and lipoprotein values that are relatively stable in adulthood undergo continuous changes during the developmental years, with most of these changes reflecting natural fluctuations that occur with growth and maturation. Therefore, a clinical classification system appropriate for youth should not consist of uniform lipoprotein thresholds that can be used at all ages to define healthy and increased risk values. This is, however, the approach used in the National Cholesterol Education Program pediatric guidelines. A recent study created the first age-specific lipid and lipoprotein thresholds for adolescents based on a large representative sample of American adolescents aged 12 to 19 years. The adolescent thresholds were linked to the health-based thresholds used in adults using growth curve modeling. Although studies are needed to validate the newly defined adolescent lipid and lipoprotein thresholds, this classification system should provide a more accurate diagnosis of dyslipidemia and associated cardiovascular health risks in adolescents.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.003 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.002 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".