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Record W2335553663 · doi:10.1021/om201133r

Factors Influencing the Outcomes of Intermolecular C–H Activations of Hydrocarbons Initiated by CpW(NO)(CH<sub>2</sub>CMe<sub>3</sub>)(η<sup>3</sup>-allyl) Complexes (Cp = η<sup>5</sup>-C<sub>5</sub>Me<sub>5</sub> (Cp*), η<sup>5</sup>-C<sub>5</sub>Me<sub>4</sub>H (Cp′))

2012· article· en· W2335553663 on OpenAlexaff
Rhett A. Baillie, Tommy Tran, Kathryn M. Lalonde, Jenkins Y. K. Tsang, M.E. Thibault, Brian O. Patrick, Peter Legzdins

Bibliographic record

VenueOrganometallics · 2012
Typearticle
Languageen
FieldChemistry
TopicOrganometallic Complex Synthesis and Catalysis
Canadian institutionsUniversity of British Columbia
Fundersnot available
KeywordsChemistryMethylcyclohexaneHydrocarbonNeopentaneIntramolecular forceMigratory insertionMedicinal chemistryLigand (biochemistry)AlkylStereochemistryDieneReductive eliminationGroup 2 organometallic chemistryPhotochemistryMoleculeOrganic chemistryTolueneCatalysis

Abstract

fetched live from OpenAlex

Gentle thermolyses of CpW(NO)(CH 2 CMe 3 )(η 3 -allyl) complexes (Cp = η 5 -C 5 Me 5 (Cp*), η 5 -C 5 Me 4 H (Cp′)) in neat hydrocarbon solutions result in the loss of neopentane from the metal’s coordination spheres and the transient formation of the 16-electron (16e) intermediate species CpW(NO)(η 2 -allene) and/or CpW(NO)(η 2 -diene). These transient intermediates can react with hydrocarbon substrates, RH (R = alkyl, aryl), to form three different types of organometallic products. The first products are the desired CpW(NO)(η 3 -allyl)(η 1 -R) complexes that result from the selective single activation of a C–H bond of RH. The second class of products involves CpW(NO)(H)[η 3 -(R)-allyl] complexes that are isomers of the CpW(NO)(η 3 -allyl)(η 1 -R) compounds resulting from an intramolecular R/allyl H exchange. Finally, the third type of products contains CpW(NO)(H)[η 3 -hydrocarbyl] species that result from three successive C–H activations of hydrocarbon substrates such as R′CH 2 CH 2 CH 3 and loss of the original allyl ligand. Just which organometallic products ultimately result from the reactions of the CpW(NO)(CH 2 CMe 3 )(η 3 -allyl) complexes with hydrocarbons depends on several factors, including the natures of the cyclopentadienyl and allyl ligands, the hydrocarbon substrates themselves, the electron density at the metal centers, and the experimental conditions employed. This article documents these dependences and identifies the optimum CpW(NO)(CH 2 CMe 3 )(η 3 -allyl) compounds and experimental conditions for effecting the selective single C–H bond activations of hydrocarbon substrates such as benzene as a representative arene and methylcyclohexane as a representative alkane. During the course of these investigations all new organometallic complexes have been characterized by conventional spectroscopic methods, and the solid-state molecular structures of several of them have been established by single-crystal X-ray crystallographic analyses.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.004
metaresearch head score (Gemma)0.005
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Science and technology studies, Scholarly communication, Open science, Research integrity, Insufficient payload (model declined to judge)
Consensus categoriesMeta-epidemiology (narrow), Science and technology studies, Research integrity, Insufficient payload (model declined to judge)
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.007
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0040.005
Meta-epidemiology (narrow)0.0080.007
Meta-epidemiology (broad)0.0090.006
Bibliometrics0.0040.009
Science and technology studies0.0030.004
Scholarly communication0.0020.005
Open science0.0080.005
Research integrity0.0040.006
Insufficient payload (model declined to judge)0.0010.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.022
GPT teacher head0.232
Teacher spread0.210 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; both teacher heads agree on what is shown here.

Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations15
Published2012
Admission routes1
Has abstractyes

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