Hospital Admissions Associated to Respiratory Viruses, 2014–2015 Season: Valencia Hospital Network for the Study of Influenza and Other Respiratory Viruses (Spain)
Bibliographic record
Abstract
Background. Burden of disease associated with respiratory viruses (RV) is poorly defined. The aim of this study was to describe the incidence of admissions with RV, by age and virus. Methods. Prospective active surveillance study of consecutive admissions with RV confirmed infection in ten hospitals (catchment area 2,351,526 inhabitants) in the Valencia region (Spain). We identified all patients admitted with symptoms possibly associated with a recent viral infection. After consent, we obtained nasopharyngeal swabs that were tested by RT-PCR. We obtained population data from the health care Population Information System. Results. From epidemiological week 45-2014 to 13-2015, we ascertained 9363 eligible admissions, 87% consented to be included, 4429 (47%) met all inclusion criteria, valid samples were available from 4423 (47%). Overall, 1689 (38%) were positive for a RV: 741 (44%) influenza, 363 (21%) rhino/enterovirus, 226 (13%) respiratory syncytial virus, 134 (8%), coronavirus, 115 metapneumovirus (7%), 79 (5%) mixed infections and 1% or less for bocavirus, parainfluenza or adenovirus. Admission rates with a RV were 1575 per 100,000 inhabitants <1 years old, 210 in those 1 to 4 years old, and 232 per 100,000 in patients aged ≥65 (figure 1). A(H3N2) was predominant (613, 83% of all influenza) with admission rates of 98 per 100,000 inhabitants <1 years old and 57, 139 and 252 admissions per 100,000 in patients 65-74, 75-84 and ≥85 years old, respectively. RSV admission rates were 679 per 100,000 inhabitants <1, 50 per 100,000 in those 1 to 4 years old, and 6, 15 and 26 per 100,000 in patients aged 65-74, 75-84 and ≥85, respectively. Rhino/enterovirus were associated with 326 admissions per 100,000 inhabitants <1 year old, 55 per 100,000 1 to 4, and 21, 53 and 87 per 100,000 in patients aged 65-74, 75-84 and ≥85, respectively Figure. Age-specific admission rates. Conclusion. The greatest burden of disease due to admissions with respiratory virus infection was observed mainly in children under one year of age with 1.6 % children in their first year of life being admitted at least once. The incidence of admissions in the group of 1 to 4 years of age was similar to that experienced in the group aged 65 or more. Disclosures. J. Puig-Barberà, Sanofi Pasteur Institution: funding for the study, Research support; A. Mira-Iglesias, Sanofi Pasteur Institution: funding for the study, Research support; M. Tortajada-Girbés, Sanofi Pasteur Institution: funding for the study, Research support; F. X. López-Labrador, Sanofi Pasteur Institution: funding for the study, Research support; Belenguer-Varea, Sanofi Pasteur Institution: funding for the study, Research support; C. Carratalà-Munuera, Sanofi Pasteur Institution: funding for the study, Research support; M. Carballido-Fernández, Sanofi Pasteur Institution: funding for the study, Research support; R. Limón-Ramírez, Sanofi Pasteur Institution: funding for the study, Research support; E. Carbonell-Franco, Sanofi Pasteur Institution: funding for the study, Research support; J. Mollar-Maseres, Sanofi Pasteur Institution: funding for the study, Research support; M. D. C. Otero-Reigada, Sanofi Pasteur Institution: funding for the study, Research support; G. Schwarz-Chavarri, Sanofi Pasteur Institution: funding for the study, Research support; J. Tuells-Hernández, Sanofi Pasteur Institution: funding for the study, Research support; V. Gil-Guillén, Sanofi Pasteur Institution: funding for the study, Research support.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.002 |
| Meta-epidemiology (narrow) | 0.001 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.001 |
| Bibliometrics | 0.001 | 0.002 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.001 | 0.000 |
| Open science | 0.001 | 0.001 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".