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Effect of wild blueberry (Vaccinium angustifolium) juice consumption on cardiovascular and inflammatory markers in male participants

2009· article· en· W2338941341 on OpenAlexaff
Gina Murphy‐Walsh, Katherine Gottschall‐Pass, Marva Sweeney‐Nixon

Bibliographic record

VenueThe FASEB Journal · 2009
Typearticle
Languageen
FieldMedicine
TopicPhytochemicals and Antioxidant Activities
Canadian institutionsUniversity of Prince Edward Island
FundersAllianz Industrie Forschung
KeywordsMedicineVacciniumAdiponectinPlaceboCrossover studyInsulin resistanceType 2 diabetesDipperInternal medicineInsulinPhysiologyEndocrinologyDiabetes mellitusBlood pressureBiologyBotany

Abstract

fetched live from OpenAlex

Wild blueberries are rich in antioxidants and may offer a novel approach to treat heart disease due to anti‐inflammatory properties. Thus, this study examined the effect of human consumption of wild blueberry juice on markers of cardiovascular disease. Fourteen middle‐aged men with cardiovascular risk factors consumed wild blueberry juice for 3 weeks in a single‐blind, randomized, placebo‐controlled, crossover intervention trial (with a 2‐week washout). Exclusion criteria included use of lipid‐altering medications or history of inflammatory disease. Compliance was monitored using 3‐day food records. Fasting blood samples were taken at the beginning and end of each treatment period, and serum analyzed. In general, results were not statistically significant. However there were trends toward an increase in adiponectin, and a decrease in serum glucose (p=0.075) and insulin concentrations in the treatment group. Insulin resistance, estimated using the homeostasis model assessment, decreased in the treatment group whereas it increased in the placebo group. Also, blueberry lowered levels of inflammatory cytokines (IL‐6, CRP, TNFα (p=0.081)). These results suggest that dietary blueberry may exhibit cardio‐protective properties in men. However, more studies with a greater sample size and longer treatment time are needed to further define efficacy and dose. [Funded by PEI WBGA and AIF]

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.003
Threshold uncertainty score0.009

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0030.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.015
GPT teacher head0.264
Teacher spread0.249 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2009
Admission routes1
Has abstractyes

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