Infants with artificially elevated pulse oximetry levels less likely to be hospitalised during an episode of mild to moderate bronchiolitis
Bibliographic record
Abstract
Design : Double-blind single-centre randomised trial. Allocation : Concealed (web-based randomisation). Blinding : Emergency department physicians, nurses, families and research nurses were all blinded to group assignment. Setting : Tertiary-care paediatric emergency department in Toronto. Patients : Previously healthy infants aged 4 weeks to 12 months diagnosed with mild to moderate bronchiolitis. Children with cardiopulmonary, neuromuscular, haematological or congenital airway anomalies, triage saturations <88%, severe respiratory distress or those transferred from other centres were excluded. Intervention : Random allocation to either true oxygen saturation or altered saturation (saturation measurements three points higher to a maximum of 100%). Outcomes : Hospitalisation within 72 h; use of supplemental oxygen in the emergency department; level of physician agreement with discharge from emergency department; length of emergency department stay; unscheduled visits for bronchiolitis within 72 h. Follow-up period : 72 h. Patient follow-up : 213 children randomised; 108 were assigned to receive true oximetry measurements and 105 to receive altered oximetry measurements. No patients discontinued the intervention or were lost to follow-up and all were therefore included in the final analysis. Patients in the true oxygen saturation group were significantly more likely to be hospitalised than those in the altered oxygen saturation group. There were no significant differences between the two groups with regard to any of the other outcomes (see table 1). View this table: Table 1 Outcome of altering oximetry on discharge Among infants presenting to an emergency department with mild-to-moderate bronchiolitis, those with artificially increased oxygen saturations were less likely … Correspondence to Dr Ian D Wacogne, Department of General Paediatrics, Birmingham Children's Hospital, Steelhouse Lane, Birmingham B4 6NH, UK; ian.wacogne{at}googlemail.com
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.003 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.001 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".