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Record W2344847967 · doi:10.1111/ajt.13843

Machine Perfusion of Donor Livers for Transplantation: A Proposal for Standardized Nomenclature and Reporting Guidelines

2016· review· en· W2344847967 on OpenAlexaff
Shanice A. Karangwa, P. Dutkowski, P. Fontes, P Friend, James V. Guarrera, James F. Markmann, Hynek Mergental, Thomas Minor, Cristiano Quintini, Markus Selzner, Korkut Uygun, Christopher J.E. Watson, Robert J. Porte

Bibliographic record

VenueAmerican Journal of Transplantation · 2016
Typereview
Languageen
FieldMedicine
TopicOrgan Transplantation Techniques and Outcomes
Canadian institutionsToronto General Hospital
FundersWellcome Trust
KeywordsMedicineStandardizationNomenclatureMachine perfusionLiver transplantationConsistency (knowledge bases)TransplantationMedical physicsIntensive care medicineComputer scienceSurgeryTaxonomy (biology)Artificial intelligence

Abstract

fetched live from OpenAlex

With increasing demand for donor organs for transplantation, machine perfusion (MP) promises to be a beneficial alternative preservation method for donor livers, particularly those considered to be of suboptimal quality, also known as extended criteria donor livers. Over the last decade, numerous studies researching MP of donor livers have been published and incredible advances have been made in both experimental and clinical research in this area. With numerous research groups working on MP, various techniques are being explored, often applying different nomenclature. The objective of this review is to catalog the differences observed in the nomenclature used in the current literature to denote various MP techniques and the manner in which methodology is reported. From this analysis, we propose a standardization of nomenclature on liver MP to maximize consistency and to enable reliable comparison and meta-analyses of studies. In addition, we propose a standardized set of guidelines for reporting the methodology of future studies on liver MP that will facilitate comparison as well as clinical implementation of liver MP procedures.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.066
metaresearch head score (Gemma)0.056
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesnone
DomainCandidate signal: Reporting · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.934
Threshold uncertainty score0.347

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0660.056
Meta-epidemiology (narrow)0.0020.001
Meta-epidemiology (broad)0.0060.007
Bibliometrics0.0120.010
Science and technology studies0.0020.007
Scholarly communication0.0080.008
Open science0.0100.005
Research integrity0.0080.013
Insufficient payload (model declined to judge)0.0010.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.050
GPT teacher head0.399
Teacher spread0.349 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

Study designNot applicable
DomainReporting
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations174
Published2016
Admission routes1
Has abstractno

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